Technology Comparison of Two Ligand-Binding Assay Platforms for Anti-Drug-Antibody Sample Testing Support for a Non-disclosed Lead Compound: MSD vs. Imperacer request reprint Immuno-PCR (IPCR) as Novel Tool for Improvement of Drug Tolerance in Immunogenicity Testing request reprint From ELISA to a...
ADA characterization assay:Confirmed positive samples will be further characterized for their binding affinity, isotyping, and other characteristics. In addition, methods to improve drug tolerance, such as affinity capture elution (ACE) and solid phase extraction with acid dissociation (SPEAD), have also...
Background: The development of an anti-drug antibody (ADA)-tolerant pharmacokinetic (PK) assay is important when the drug exposure is irrelevant to toxicity in the presence of ADA. We aimed to develop and validate an ADA-tolerant assay for an exatecan-based antibody鈥揹rug...
Serum testosterone concentrations were measured using the DPC Coat-A-Count RIA kit, which has an intra- and interassay coefficient of variation (CV) of <10% while sex hormone-binding globulin (SHBG) were measured by ELISA technique (DRG Diagnostics, Marburg, Germany). We calculated the ...
assay insensitive to haemoglobin variants is used insomeone with a haemoglobinopathy. Discrepanciesbetween measured HbA1clevels and measured or reportedglucose levels should prompt consideration that one ofthese may not be reliable [52, 53].Regular blood glucose monitoring (BGM) may help withself-...
4 & Robert A. Gabbay 5 & Jennifer Green 6 & Nisa M. Maruthur 7 & Sylvia E. Rosas 8 & Stefano Del Prato 9 & Chantal Mathieu 10 & Geltrude Mingrone 11,12,13 & Peter Rossing 14,15 & Tsvetalina Tankova 16 & Apostolos Tsapas ...
糖尿病指南diabetesglucosediabetictoacidosis StandardsofMedicalCareinDiabetes—2010 AMERICANDIABETESASSOCIATION D iabetesisachronicillnessthatre- quirescontinuingmedicalcareand ongoingpatientself-management educationandsupporttopreventacute complicationsandtoreducetheriskof long-termcomplications.Diabetescareis complexand...
Oral Glucose Tolerance Test (OGTT) was conducted on normoglycemic rats, and anti-hyperglycemic test on diabetic rats; five groups with five rats each were constituted. Group 1: negative control was treated with vehicle; Group 2, Group 3, and Group 4 were treated with increasing water-ethanol...
Genes for Plant Abiotic Stress || Genes and Gene Regulation for Low-Temperature Tolerance Abiotic stresses caused by drought, salinity, toxi... MA Jenks,AJ Wood - Genes for Plant Abiotic Stress || Genes and Gene Regulation for Low-Temperature Tolerance 被引量: 42发表: 2009年 Soluble Polychela...
IMMUNE TOLERANCE INDUCTION AND ERADICATION OF ANTI-DRUG ANTIBODIES (ADA) TO THERAPEUTIC FACTOR VIIIMethods for immune tolerance induction and eradication of anti-drug antibodies to therapeutic Factor VIII are disclosed.