Acylcarnitinestandem mass spectrometryinherited metabolic diseasemetabolomicsfatty acid oxidationThe acylcarnitine profile is a diagnostic test for inherited disorders of fatty acid and branched-chain amino acid catabolism. Patients with this type of metabolic disorder accumulate......
The results obtained with the Kruskal–Wallis test referred to all the newborn and were biased by the large number of vaginally delivered term-born infants. Respiratory diseases and AC profile. No associations were found between RDS or BPD and AC concentrations, not even when intra-group ...
摘要: The acylcarnitine profile is a diagnostic test for inherited disorders of fatty acid and branched-chain amino acid catabolism. Patients with this type of metabolic disorder accumulate...关键词: Acylcarnitines tandem mass spectrometry inherited metabolic disease metabolomics fatty acid oxidation ...
Acylcarnitine profile analysis Abstract Disclaimer: These Technical Standards and Guidelines were developed primarily as an educational resource for clinical laboratory geneticists to help them provide quality clinical laboratory genetic services. Adherence to these standards and guidelines is voluntary and does ...
Plasma samples collected at baseline and after eight weeks of treatment with citalopram or escitalopram were profiled for short-, medium- and long-chain acylcarnitine levels using AbsoluteIDQ®p180-Kit and LC-MS. Linear mixed effects models were used to examine whether acylcarnitine levels ...
www.nature.com/scientificreports OPEN Altered serum acylcarnitine profile is associated with the status of nonalcoholic fatty liver disease Received: 7 May 2019 Accepted: 12 July 2019 Published: xx xx xxxx (NAFLD) and NAFLD-related hepatocellular carcinoma Kenichiro Enooku1, Hayato Nakagawa1, ...
To elucidate lipid-related genes in GBC tumorigenesis, microarray analysis was performed to profile the gene expression of nine paired tumor tissues and adjacent tissues (GES76633) [24]. Gene ontology enrichment and KEGG analyses showed a significant decrease in FAO in GBC tissues (Fig. 1C and ...
Patients with peroxisomal biogenesis disorders (PBDs) have an abnormal profile of circulating acylcarnitines (i.e. elevated C16:0-DC-, C18:0-DC-, C24:0-, C26:0-carnitine). We developed an ESI–MS/MS method for quantification of urine acylcarnitines and tested its reliability for the diagno...
AC concentration during an oral glucose tolerance test (OGTT) To evaluate whether the plasma AC profile can be used as a marker of AC content in tissues, the AC content was measured during an OGTT in the heart, hindlimb muscles and liver, and the possible association of plasma AC concentrati...
Postnatal Changes in Neonatal Acylcarnitine Profile JOCHEN MEYBURG, ANDREAS SCHULZE, DIRK KOHLMUELLER, OTWIN LINDERKAMP, AND ERTAN MAYATEPEK Department of Neonatology [J.M., O.L.] and Division of Metabolic Diseases, Department of General Pediatrics [A.S., D.K., E.M.], University Children'...