A-145-1MLAcylcarnitines Mix 3 (C8:1,C10:1,C12:1,C14:1,C14:2,C16:1,C18:1,C18:2)/酰基肉碱混合标准溶液3(C8:1,C10:1,C12:1,C14:1,C14:2,C16:1,C18:1,C18:2) 100-200 ug/mL in Methanol:1% aqueous formic acid (90:10) (v/v) | Certified Reference MaterialAcylcarnitines Mix 3 ...
In addition, long-chain acylcarntines including AC18:1 were positively correlated with serum levels of inflammatory cytokines. Although none of the acylcarnitine species were independently associated with the presence of HCC, (AC16:0鈥 +鈥堿C18:1)/AC2:0, an index for the diagnosis of carnitine...
The serum concentrations of long-chain ACC tetradecenoylcarnitine (C14:1) and octadecenoylcarnitine (C18:1) concentrations were greater on d 1 and 21 compared with d -21. Muscle carnitine remained unchanged, whereas short- and medium-chain ACC, including propenoylcarnitine (C3:1), hydroxybutyryl...
Plasma kynurenine (KYN) and acylcarnitines (C0, C4, C6, and C18:1-OH) were identified with higher concentrations in older Taiwanese adults with possible sarcopenia and S compared to the Con group. After multivariable adjustment, the data indicate that age, BMI, and butyrylcarnitine (C4) are ...
When analysis was performed at the level of individual metabolites, C16, C16:1, C18, and C18:1 had the greatest associations with both exercise capacity and outcomes, with higher levels associated with worse outcomes. Similar associations with time to the primary clinical outcome were not found ...
Acylcarnitines associated with fat mobilization and FAO were significantly increased in condition B: long-chain acylcarnitines (i.e., C18:1, -70%), metabolites from active but incomplete FAO [i.e., C14:l (161%) and C14:2 (102%)] and medium- to short-chain acylcarnitines [i.e., C2...
Separation is obtained using a methanol/water gradient with a C18 BEH, 1 × 100 mm, 1.7 μm UPLC column, at 60 °C; run time is less than 10 min. The isomers are detected with a Quattro Premier triple quadrupole, with electrospray ionization in positive ion mode. Results Intra-day ...
In the present study, we evaluated levels of acylcarnitine with various chain lengths (C18 to C2), free carnitine, and their ratios in 175 infants who tested positive for VLCAD deficiency with C14:1 and C14:1/C2 ratios. Our analyses indicated that the ratios of C14:1 to medium-chain ...