Structural basis for mechanistic similarities and differences. Eur. J. Biochem. 271 : 483 -493.Kim JJ, Miura R (2004) Acyl-CoA dehydrogenases and acyl-CoA oxidases. Structural basis for mechanistic similarities
Acyl-CoA dehydrogenases and acyl-CoA oxidases. Structural basis for mechanistic similarities and differences. Eur. J. Biochem. 271 : 483 -493.Kim JJ, Miura R (2004) Acyl-CoA dehydrogenases and acyl-CoA oxidases. Structural basis for mechanistic similarities and differences. Eur J Biochem 271:...
Acyl-CoA dehydrogenases and acyl-CoA oxidases are two closely related FAD-containing enzyme families that are present in mitochondria and peroxisomes, respectively. They catalyze the dehydrogenation of acyl-CoA thioesters to the corresponding trans-2-enoyl-CoA. This review examines the structure of me...
Furthermore, we provide evidence that acyl-CoA dehydrogenases (ACADs) are bona fide peroxisomal proteins in fungi and mammals and together with acyl-CoA oxidases (ACOX) belong to the basic enzymatic repertoire of peroxisomes. A genome comparison with baker's yeast and human gained new insights ...
acyl‐CoA oxidase α,β‐dehydrogenationmechanismsAcyl-CoA dehydrogenases constitute a family of flavoproteins that catalyze the α,β-dehydrogenation of fatty acid acyl-CoA conjugates. While they differ widely in their specificity, they share the same basic chemical mechanism of α,β-dehydrogenation....
7.03.3.2Acyl-CoA Dehydrogenases and Oxidases Acyl-CoA dehydrogenases (ACADs),flavoproteinsfound in the mitochondria, are involved in β-oxidation of fatty acids. Currently, there are five types ofACADsclassified according tosubstrate specificity. Short-chainACAD(SCAD), medium-chain ACAD (...
Twitter Google Share on Facebook ac·yl·ad·e·nyl·ate (as'il-ă-den'il-āt), A compound in which an acyl group is combined with AMP by elimination of H2O from the carobxyl group and of the phosphate residue of AMP, usually in the initial form of ATP; inorganic pyrophosphate is...
However, culture in the presence of HCCL and propionate (2 mmol/L) resulted in accumulation of methylmalonyl-CoA and a 59% increase in total CoA content. The combination of HCCL (1 mg/L) and propionate (0.5 mmol/L), but not HCCL alone, increased the rate of (14C)pantothenic acid ...
acyl-CoA dehydrogenaseacyl-CoA oxidase α,β-dehydrogenationmechanismsAcyl-CoA dehydrogenases constitute a family of flavoproteins that catalyze the 卤,-dehydrogenation of fatty acid acyl-CoA conjugates. While they differ widely in their specificity, they sh...
The acyl-CoA oxidases/dehydrogenases of the three algae differ not only by their capability for oxidation of acyl-CoA of different chain lengths but also with regard to their Km values and substrate specificities. Indications were obtained that the oxygen is reduced to water rather than to H2O2...