Oxidation of ketones by H2O2 in aqueous ammonia in the presence of the sodium salts of EDTA or 1,2-diaminocyclohexane tetra acetate as catalyst affords 1,2,4-dioxazolidines (153) in high yield (Equation (12)) 〈83JAP83121284, 88JAP8891363, 83JAP8318372, 91JMOC383, 91MI 413-02〉. (...
The reaction was incubated for 15 min at 37 °C, and 10 μl of the reaction was spotted on a Silica Gel H plate and developed with 1-butanol:methanol:ammonia:water (5:4:2:1, v/v/v/v). The reaction with [14C]acetyl-CoA (0–320 μM) (specific activity 20 mCi/mmol) was ...