ISCHEMIAMEDICAL suctionFIBRINOLYTIC agentsCOMPUTED tomographyMechanical thrombectomy is a safe and effective treatment in patients with acute ischemic stroke caused by large vessel occlusions. However, in rare cases, the procedure may be challenging due to the composition of the embolus. We describe a ...
Stroke ranks as the second leading cause of death worldwide and is a major contributor to disability.[2][3][4]Stroke imposes a considerable financial burden due to the costs associated with prehospital, hospital, and posthospital care.[5][6][7] Understanding that the potential for achieving ...
Acute ischemic stroke (AIS) accounts for more than half of stroke cases and results in severe outcomes from physical disabilities, mental disorders to death. Timely treatment could save brain tissue as more as possible. However, the treatment for AIS should take many factors into consideration, su...
such as fatigue or changes in mental status8,9, and having a higher risk of delays in hospital arrival10,11. Also, women feature a higher risk of cardioembolic stroke due to atrial fibrillation12, which may contribute to the often-observed higher acute ischemic stroke (AIS) severity ...
Abstract The development of ischemic brain injury depends upon the severity and duration of ischemia [9, 13]. Compromised brain tissues may recover if blood flow is restored after a brief duration of ischemia [4, 13, 14, 17, 24, 27]. This concept has led to therapeutic attempts to restore...
The high mortality and disability rates associated with ischemic stroke are closely related to the extent of neuronal necrosis occurring after cerebral ischemia, where neurons in the ischemic core gradually die (infarct) due to persistent ischemia or ischemic–reperfusion injury. The periphery of the ...
Senescent cells are capable of expressing a myriad of inflammatory cytokines and this pro-inflammatory phenomenon is known as senescence-associated secretory phenotype (SASP). The contribution of this phenomenon in brain ischemia was scarce. A mouse mode
Estrogens as protectants of the neurovascular unit against ischemic stroke. Curr Drug Targets CNS Neurol Disord. 2005;4: 169–77. Article PubMed CAS Google Scholar Merchenthaler I, Dellovade TL, Shughrue PJ. Neuroprotection by estrogen in animal models of global and focal ischemia. Ann N Y...
Unless imaging can be done on the spot [as by mobile stroke unit (MSU) ambulances], it will remain uncertain whether the stroke is caused by ischemia [80%, acute ischemic stroke (AIS)] or hemorrhage [intracerebral hemorrhage (ICH)]. It is possible, however, to confidently grade the ...
Y., et al.. (2002). Computed tomographic findings in patients undergoing intra-arterial thrombolysis for acute ischemic stroke due to middle cerebral artery occlusion: results from the PROACT II trial.Stroke33: 1557–1565,https://doi.org/10.1161/01.str.0000018011.66817.41.Search in Google Schola...