Stroke ranks as the second leading cause of death worldwide and is a major contributor to disability.[2][3][4]Stroke imposes a considerable financial burden due to the costs associated with prehospital, hospital, and posthospital care.[5][6][7] Understanding that the potential for achieving ...
such as fatigue or changes in mental status8,9, and having a higher risk of delays in hospital arrival10,11. Also, women feature a higher risk of cardioembolic stroke due to atrial fibrillation12, which may contribute to the often-observed higher acute ischemic stroke (AIS) severity ...
Inflammatory Cytokines are in Action: Brain Plasticity and Recovery after Brain Ischemia Due to Delayed Melatonin Administration Objectives: Post-ischemic inflammation leads to apoptosis as an indirect cause of functional disabilities after the stroke. Melatonin maybe a good candidat... U Kilic,B Elib...
Ischemia-modified albumin in acute stroke.[J].Cerebrovascular diseases 2007,2/3(2/3).Abboud H,Labreuche J,Meseguer E. Ischemia-modified albumin in acute stroke[J].Cerebrovascular Diseases,2007,(2-3):216-220.Lavallee PC,Mazighi M,Dehoux M,etc.Ischemia-modified albumin in acute stroke.[J]...
The high mortality and disability rates associated with ischemic stroke are closely related to the extent of neuronal necrosis occurring after cerebral ischemia, where neurons in the ischemic core gradually die (infarct) due to persistent ischemia or ischemic–reperfusion injury. The periphery of the ...
ofp16andp21in senescence and inflammation and could have implications in ischemic stroke. In transient forebrain ischemia, elevated p21 might be a response to the ischemic insult to protect the neurons by arresting them in first steps of the cell cycle. The p21 expression is enhanced in surviving...
Insulin-dependent diabetes mellitus (IDDM) is associated with an increased incidence of heart failure due to several factors, and in some cases a specific cardiomyopathy has been suggested. Objectives. This study sought to assess the mechanisms of exercise induced left ventricular (LV) dysfunction in...
Tissue injury and stress activate endogenous mechanisms to restore homeostatic balance and prevent further damage by upregulating the synthesis of lipid signalling molecules, including palmitoylethanolamide (PEA), which has positive neuroprotective effects and reduces inflammatory events due to ischemia reperfu...
For more than a decade at the University of California at Los Angeles, an intensive imaging strategy has been used to establish stroke diagnosis, delineate early patterns of cerebral ischemia, and monitor response to various reperfusion techniques. Angiographic findings before thrombolysis have ...
The penumbra is the region of brain surrounding the infarct area where the blood supply is significantly reduced, but energy metabolism is maintained due to collateral flow. The viability of this area is dependent on both the severity and duration of ischemia. If blood flow is rapidly restored,...