Asthma exacerbations account for 75,000 hospital admissions in the UK and Republic of Ireland. Asthma still accounts for in excess of 1,300 UK deaths. Risk factors for fatal asthma include poorly controlled disease, inappropriate medical management and adverse behavioural and social factors. Asthma ...
Acute severe asthma remains an important medical emergency with a risk of respiratory arrest and death. It requires prompt clinical assessment with aggressive medical management. Acute severe asthma is the most common presentation of life threatening asthma in which more than 70% patients are t...
Risk factors for morbidity in mechanically ventilated patients with acute severe asthma Am. Rev. Respir. Dis., 146 (3) (1992), pp. 607-615, 10.1164/ajrccm/146.3.607 View in ScopusGoogle Scholar [18] C. Chang, D. Yates Use of early extra-corporeal membrane oxygenation (ECMO) for severe...
In an acute severe asthma episode, close observation plus aggressive administration of bronchodilators (SABAs plus ipratropium bromide via a nebulizer driven by oxygen) and oral or intravenous corticosteroids are necessary to arrest the progression to severe hypercapnic respiratory failure leading to a dec...
However, in a very small group of patients, asthmatic attacks can be fatal (near-fa- tal asthma). Severe asthmatic attacks can be resistant to therapy in this patient group, and mechanical ventilation therapy is called for in some of these patients. Patients with asthma are at a risk of...
8 and larger pulse oximeter saturation reduction after exercise at low altitude among young adults.9 A nested case-referent study among miners has shown that past AMS and current smoking are strong risk factors for severe AMS.10 A review article has Received: 21 August 2023 Accepted: 16 ...
Linoleic acid metabolite drives severe asthma by causing airway epithelial injury. Sci Rep. 2013;3:1349. Article PubMed PubMed Central Google Scholar Rahman M, et al. Comparable response following exposure to biodiesel and diesel exhaust particles in advanced multicellular human lung models. Toxics...
A 56-year-old woman presented to our hospital with acute severe asthma. As a consequence of severe refractory airflow limitation, moderate hypercapnia ensued for several days. Unexpectedly, the patient died as a result of brain stem herniation, in the absence of hypoxaemia, arterial hypotension or...
Sex-specific genetic, hormonal and immune risk factors may help explain why more men have severe outcomes from acute SARS-CoV-2 infection, while more women are affected with PASC [108]. In addition, social determinants of health are emerging as important factors in patients’ access to care ...
More severe AKI is associated with poorer outcomes. However, these classification systems all evaluate the magnitude of serum creatinine increase and/or decrease in urine output, without considering factors such as underlying diseases and duration of AKI. Lately, the duration of kidney injury has ...