Risk of Acute Myeloid Leukemia in Adults with Primary Immune Thrombocytopenia Treated with Thrombopoietin Receptor Agonists: A French Nationwide Population-Based Study Introduction Immune thrombocytopenia (ITP) is a rare autoimmune disease due to platelet destruction and impaired megacaryopoiesis. ...
Type of hematological malignancy was determined using ICD-10 codes and was first classified in 11 categories: acute myeloid leukemia (AML), acute lymphoid leukemia (ALL), unknown type of acute leukemia, chronic lymphoid leukemia (CLL), multiple myeloma (MM), non-Hodgkin’s lymphoma (NHL), Hodg...
T-lymphoblastic lymphoma/leukemia are always positive for CD3; other T-cell lineage–associated markers CD2, CD5, CD7 are almost equally sensitive but can be seen in B and myeloid lineages. In addition to the immature markers TdT and CD34, CD1a can also be seen in T-lymphoblastic ...
ICD-9-CM procedure code that may be associated with chronic kidney disease (39.27, 39.42-3, 39.50, 39.53, 39.93-4, 55.52-4, 55.6; eTable 1 in the Supplement); had an ICD-9-CM procedure code for dialysis (39.95 or 54.98) during the first 3 days of hospitalization; or had an ICD-...
Genetic alterations were present in 40.6% of B-cell and 69% of myeloid. The genetic alteration was related to the patient's short-term evolution in type B leukemias but not in myeloid. In B-cell leukemia, the cases with the altered MLL gene died in less than one month; cases with t(...
Background: Recent evidence demonstrated that the treatment of acute myeloid leukemia (AML) cells with daunorubicin (DNR) but not cytarabine (Ara-C) results in immunogenic cell death (ICD). In the clinical setting, chemotherapy including anthracyclines and Ara-C remains a gold standard for AML tr...