ALL is also known as acute lymphocyticleukemiaor acute lymphoid leukemia. ”Acute” means it gets worse quickly. It’s a rare type of leukemia, or blood cancer, in adults but the most common type in children. Acute lymphoblastic leukemia invades your blood and can spread to other organs, su...
Despite recent diagnostic improvements, more precise risk stratification, chemotherapy intensification, better supportive care and broader indications for hematopoietic cell transplantation (HSCT), survival in pediatric AML is still significantly below the survival rates of acute lymphoid leukemia (ALL) in ...
Progress in the understanding of the biology and therapy of acute myeloid leukemia (AML) is occurring rapidly. Since 2017, nine agents have been approved for various indications in AML. These included several targeted therapies like venetoclax, FLT3 inhi
T cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy arising from aberrant proliferation of immature T cell progenitors and accounts for about 15% of pediatric ALL cases1. The current risk-adapted, multiagent chemotherapeutic regimen has led to an overall survival rate exceeding ...
significantly longer than mice engrafted with AML cells but treated with vehicle only (median survival: 64 vs 50 days, P=0.0067; Figure 3e), suggesting that AML engraftment- or AML-derived exosome-induced DKK1 expression likely suppressed osteoblast differentiation and supported enhanced leukemia ...
Ethnicity and cure rates of Texas children with acute lymphoid leukemia BackgroundDespite advances in treatment, survival from acute lymphoblastic leukemia (ALL) remains lower among non-White children than White children in the... MH Hord,TL Smith,SJ Culbert,... - 《Cancer》 被引量: 0发表: ...
Acute lymphoid leukemia (ALL) is a type of hematological neoplasm that affects the precursor cells of strains B, T and NK, with a higher incidence in the pediatric range. The pathophysiology of ALL is characterized by chromosomal abnormalities and genetic alterations involved in the differentiation ...
Acute lymphoid leukemia AML: Acute myeloid leukemia ANSM: Agence Nationale de Sécurité du Médicament et des Produits de Santé AP: Acute pancreatitis ARDS: Acute respiratory distress syndrome ARF: Acute respiratory failure CIs: Confidence intervals CLL: Chronic lymphoid leukemia CMML: Chro...
Acute lymphocytic leukemia (also called acute lymphoblastic leukemia; ALL) is a neoplasm of immature B- or T-cells (lymphoblasts). In the most recent World Health Organization (WHO) classification of hematopoietic and lymphoid tumors, it is classified under “precursor B-cell lymphoblastic...
In contrast to chronic leukemias, both acute leukemia types are characterized by the accumulation of immature cells of different blood lineages (lymphoid versus myeloid). As the cells of origin for both AML and ALL are premature in contrast to other hematopoietic malignancies such as mutated CLL ...