Childhood acute lymphoblastic leukemia (ALL) is a heterogeneous disease with respect to immunophenotype and karyotype of the blast cells, and so the biological features of the cells appear to have a strong influence on the prognosis. DNA analysis by flow cytometry (FCM) is an ideal way to ...
Genome-wide methylation maps of acute lymphoblastic leukemia We performed whole-genome bisulfite sequencing (WGBS) on diagnostic leukemic cells from 82 patients representing three subtypes of childhood B-ALL (Philadelphia chromosome (Ph)-like34, DUX4-rearranged/ERG-deregulated19 and hypodiploid20 ALL) ...
Acute lymphoblastic leukemia (ALL) is a type of blood cancer. Learn more about the causes, risk factors, symptoms, diagnosis, treatment types, and prognosis for acute lymphoblastic leukemia.
acute lymphoblastic leukemia- acute leukemia characterized by proliferation of immature lymphoblast-like cells in bone marrow, lymph nodes, spleen, and blood; most common in children acute lymphocytic leukemia acute leukemia- rapidly progressing leukemia ...
This paper reported a case of a child with acute lymphoblastic leukemia complicated with CMV retinitis and reviewed the related literature of CMV retinitis to make a further understanding of this kind of disease for clinicians. 展开 关键词: 巨细胞病毒性视网膜炎;急性淋巴细胞性白血病;儿童 ...
High Ambient Temperatures in Pregnancy Related to Childhood Leukemia Risk Gayle Turim Dickstein When the mercury outside ascends too high early in pregnancy, the risk of pediatric acute lymphoblastic leukemia may rise as well; results also show greater impacts on Latino populations. ...
We have investigated the deletion and methylation status of MTS1 and MTS2 in childhood acute lymphoblastic leukemia (ALL) of both T-cell (17 cases) and B-cell phenotypes (29 cases), and p16and p15mRNA expression in 36 of these cases. Biallelic or monoallelic loss of both MTS1 and MTS2...
In the pediatric population, B-acute lymphoblastic leukemia (B-ALL) is the most prevalent childhood hematological malignancy, as well as the leading cause of childhood cancer-related mortality. Advances in cytogenetics utilizing array-based technologies
Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults, with an incidence of over 6500 cases per year in the United States alone. The hallmark of ALL is chromosomal abnormalities and genetic alterations involved in differen
Prenatal origin of TEL- AML1-positive acute lymphoblastic leukemia in children born in California. Genes Chromosom Cancer. 2003;37(1):36-43.McHale CM, Wiemels JL, Zhang L, et al. Prenatal origin of TEL-AML1- positive acute lymphoblastic leukemia in children born in California...