The classification system used for this leukemia is the Rai system, which is a clinical staging system based on absolute lymphocyte count and presence of lymphadenopathy, splenomegaly, anemia, and thrombocytopenia. Typically, CLL is an indolent disease. Adults with low-stage disease with white blood...
Introduction Life expectancy in elderly patients with acute myeloid leukemia (AML) is a function of age, disability, and co-morbidity, combined with leukemia characteristics. There is currently no consensus regarding the optimal therapeutic strategy for older adults with AML. Although selected older ...
Treatment of older adults with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) is challenging because of disease morbidity and associated treatments. Both diseases represent a genetically heterogeneous group of disorders primarily affecting older adults, with treatment strategies ranging from...
Today, ASH published new guidelines to help older adults with acute myeloid leukemia (AML) and their health care providers make critical care decisions, including if and how to proceed with cancer treatment and the need for blood transfusions for those in hospice care. Each year, nearly 20,000...
Acute myeloid leukemia (AML) presents in all ages but is mainly a disease of the elderly with a median age of 69 years in the white US population of the Surveillance, Epidemiology, and End Results database.1 Age has a major impact on the management and outcome for patients with AML. Eld...
intensive chemotherapy in acute myeloid leukemia: a project of SIE, SIES and GITMO group on a new tool for therapy decision making Leukemia (2013) 27, 997–999; doi:10.1038/leu.2012.303 Acute myeloid leukemia (AML) is a disease of older adults, with a median age at diagnosis over 65 ...
Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood. 2010;115:453–74. Article CAS Google Scholar Download references Acknowledgements The authors would like to acknowledge and thank Lucinda ...
Acute lymphoblastic leukemia: Past and present Acute lymphoblastic leukemia (ALL) is a rare neoplasm in adults. Its treatment has seen dynamic developments ranging from the discovery of first compounds ... C Sálek,D Sponerová,JS Maaloufová - 《Vnitr̆ní Lékar̆ství》 被引量: 9发表:...
Viruses are obligate intracellular pathogens that cause infection in susceptible host cells. Virus infections could be lytic, chronic, latent or immortalizing. Viruses causing latent infection are associated with high morbidity and mortality worldwide. The human body is protected from viral infection by...
Acute lymphoblastic leukemia (ALL) is the commonest childhood malignancy, accounting for approximately 80% of leukemia in the pediatric group, and its etiology is unknown. This neoplasia is characterized by male predominance, high-risk features and poor outcome, mainly in recurrence patients and adul...