chemical warfaresulfur mustardnitrogen mustardebselenaminoguanidineOne of the most important chemical warfare agents, sulfur mustard (SM) causes crucial acute and chronic toxic effects. Lung, skin, eye and kidneys are the most affected organs. In this work, it was investigated if increased nitric ...
Christensen, I. M. A.; Storgaard, M. S.; Fauser, P.; Hansen, S. F.; Baatrup, E.; Sanderson, H. Acute toxicity of sea-dumped chemical munitions: Lumnating the environmental toxicity of legacy com- pounds. Global Security: Health, Science and Policy 2016, 1, 39-50....
Medicilon's acute toxicology test is based on the knowledge of the test substance, following the principle of "specific analysis of specific problems", and selecting a reasonable test method according to the structural characteristics, physicochemical pr
When it is used with a chemical that has a high probability of being very toxic to D. magna (LC50< 0.22 mg/L), the test provides considerable information if it is positive, virtually giving evidence of toxicity to the rat (with a probability of 0.83). On the other hand, a negative ...
Chemical acute oral toxicity is an important end point in drug design and environmental risk assessment. However, it is difficult to determine by experiments, and in silico methods are hence developed as an alternative. In this study, a comprehensive data set containing 12,204 diverse compounds wi...
Hydroethanolic preparations of the botanical species Acmella oleracea L. are used in the north of Brazil for the treatment of various diseases. However, few studies have been conducted to evaluate the toxicity of this species. The objective of this study was to evaluate the acute toxicity of th...
The third generation displays lower toxicity, high biodegradability, and biological activity, but is less suitable as a solvent. In addition to its optimal physico-chemical properties, the use of ILs has also been highlighted by the introduction of European Union environmental laws, specifically REACH...
Chemical and radiological toxicities related to uranium acute exposure have been widely studied in nuclear fuel workers and military personnel. It is well known that uranyl nitrate induces acute renal failure (ARF). However, the mechanisms of this metal-induced injury are not well defined at the ...
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In summary, the Elsholtzia genus, with its extensive historical use and variable chemical composition, poses intriguing questions about its effects on living organisms and its safety. The following research endeavors to address these questions through a rigorous evaluation of toxicity, shedding light on...