grid.266102.10000 0001 2297 6811Department of AnatomyUniversity of California 513 Parnassus Avenue, HSW-1301 94143-0452 San Francisco California, CA USANature Publishing Group UKOncogeneSternlicht MD, Bissell MJ, Werb Z. 2000. The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor ...
aSchematic of the metabolite library screening strategy.bThe metabolite library screening results were exhibited as the relative viability of metabolite-treated cells versus vehicle-treated cells. After cell seeding, the A549 cells were pre-incubated with the metabolites contained in the library (MCE HY...
may have advantages over monotherapy for the treatment of ischemic disorders. The combination might be a promising avenue for PAD. The lack of direct permeability-enhancing effects of ManN may prove valuable, since it is expected to result in less edematous tissues. In this context, damage to lu...
Mechanisms underlying low-penetrance, common, non-protein coding variants in breast cancer risk loci are largely undefined. We showed previously that the non-protein coding mammary carcinoma susceptibility locus Mcs5a/MCS5A modulates breast cancer risk in rats and women. The Mcs5a allele from the Wi...
Additionally, in the context of brain tumors, targeting mTOR activation is considered a potent therapeutic avenue [15,33]. However, given the complex nature of this signaling pathway comprising two molecular distinct signaling branches, enabling the compensation of signal loss from either of the two...