Active DNA demethylation in mammals is achieved through TET-mediated oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC), followed by replication-dependent dilution of oxidized 5mC or thymine DNA glycosylase (TDG)-mediated ...
This target provided an attractive initial test of our selection system, since it exhibits substantial sequence identity with a second sequence in the human genome (within the homologous CCR2 gene), and the availability of highly active and specific published reagents22 for this target would provide...
Although several investigations have sug-gested the presence of intracellular 63Ni-binding macromolecules, little is known regarding their identity or properties (29,32,86,90,92,94). The kinetics of 63Ni(II) metabolism in rodents have been described by two-compartment models (84,88,89,93). ...
Serine protease inhibitors (serpins) participate in the regulation of inflammation, blood coagulation, and complement activation in humans. This research aimed to identify and characterize such inhibitors of the human liver fluke Opisthorchis viverrini.
These strains were reference strains and their identity was confirmed using the VITEK 1 automatic system. Anti-biofilm tests were performed for all compounds investigated, regardless of their activity as direct antimicrobial agents, as it was this paper's aim to obtain and to prove that the new ...
{ "@context": "https://identity.foundation/.well-known/contexts/did-configuration-v0.0.jsonld", "linked_dids": [ "eyJhbG..token1...<SNIP>...", "eyJhbG..token2...<SNIP>..." ] } Generate DID document This call generates the DID Document used for DID:WEB identifiers. After generat...