Active genotype–environment correlation starts around the ages of 8-9 and is when children begin to seek out situations and environments ('niches') that are compatible with their genotype. These niches that are chosen will strengthen the gene expression. ...
trap system reveals a positive correlation between efficient KRAB/KAP1-mediated repression of trapped promoters and i) a gene-richer and transcriptionally more active genomic context, ii) a more euchromatic environment, and iii) the pre-existence of some repressive marks at and around the promoter....
GENOTYPE-environment interactionRICEGENETIC regulationGENETIC correlationsInsight into high-resolution three-dimensional genome organization and its effect on transcription remains largely elusive in plants. Here, usinga long-read ChIA-PET approach, we map H3K4me3- and RNA polymerase II (RNAPII)-associated...
Regulation of high-density loci harboring genes with different cell-specificities remains a puzzle. Here we investigate a locus that evolved through gene duplication and contains eight genes and 20 candidate regulatory elements, including one super-enhan
Also, more advanced query strategies based on reinforcement learning and deep learning, along with query strategies under the realistic environment setting, are presented. After a rigorous mathematical analysis of AL strategies, this work presents a comparative analysis of these strategies. Finally, ...
The correlation between the two cell subsets was calculated, and a heatmap was drawn in which the two highly correlated cell subsets had relatively similar gene expression patterns. These may be the same cell type, providing some guidance for the identification of artificial cell subpopulations (...
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The cell nucleus stores the genetic material essential for life, and provides the environment for transcription, maintenance, and replication of the genome. Moreover, the nucleoplasm is filled with subnuclear bodies such as nucleoli that are responsible for other vital functions. Overall, the nucleus...
Limitations of BONCAT include the diversity of amino-acid uptake mechanisms in the environment, the potential for artificial growth stimulation following addition of amino acids and suppression of signal when environmental concentra- tions of amino acids are high. Aside from these potential The ISME ...
Because pHluorin is quenched in the low pH granule environment, it becomes visible only upon fusion, generating a transient burst of fluorescence that reveals the position of the degranulation site within the IS. When CTLs expressing pHluorin-Lamp1 were imaged on ICAM-spot, Antigen-spot, or ...