Below pH 5, pepsinogen is self-cleaved to produce active pepsin [10]. Pepsin is a monomeric, two domain, mainly β-protein, with a high percentage of acidic residues (43 out of 327) leading to a very low pI. The catalytic site is formed by two aspartate residues, Asp32 and Asp215,...
(1999). Con- tribution of a prosegment lysine residue to the function and structure of porcine pepsinogen A and its active form pepsin A. Eur. J. Biochem. 261, 746-752.Richter C,Tanaka T,Koseki T.Contribution of a Prosegment Lysine Residue to the Function and Structure of Porcine ...
Pepsin is a digestive enzyme; it is extracted from Pepsinogen under PH 1.5-5.0 and the pepsinogen is secreted by the stomachcell.Pepsin can decompose the solidified proteins into peptone by effect of stomach acid, but it can not go any further to aminoacid.Pepsin is the main digestive enzyme...
1999. Contribution of a prosegment lysine residue to the function and structure of porcine pepsinogen A and its active form pepsin A. Eur J Biochem 261: 746-752.Richter C, Tanaka T, Koseki T, Yada RY (1999) Contribu- tion of a prosegment lysine residue to the function and structure ...