Protein C is a vitamin K-dependent plasma protein zymogen whose genetic mild or severe deficiencies are linked with risk for venous thrombosis or neonatal purpura fulminans, respectively. Studies over past decades showed that activated protein C (APC) inactivates factors (F) Va and VIIIa to down...
蛋白C(protein C,PC)是一种维生素K依赖性酶原,主要在肝脏中合成,在生理情况下,凝血酶-血栓调节蛋白复合物可水解蛋白C,形成活化蛋白C(Activated Protein C, APC),APC主要作用是活化后可灭活凝血因子Ⅷa与凝血因子Ⅴa,抑制血液凝固。 蛋白质C的结构域示意图:GLA =含有γ-羧谷氨酸残基的区域,EGF =含有与人表皮生...
Activated Protein C Protein C is an important anticoagulant and anti-inflammatory protein. The main effect of protein C is to reduce the production of thrombin, by inactivatingfactors Vaand VIII. Thrombin is proinflammatory,procoagulant, andantifibrinolytic.28In addition, protein C inhibits the influen...
Description:Activated Protein C (390-404), human是一种维生素K依赖的丝氨酸蛋白酶活化蛋白C (APC)的多肽片段,序列中含有15个氨基酸,可抑制APC的抗凝血活性。 Activated Protein C (390-404), human is a peptide fragment of Vitamin K dependent Serine protease activated protein C (APC), which contains 15...
英文名称: Activated Protein C (PROC), His-tag 总访问: 89 国产/进口: 进口 半年访问: 18 产地/品牌: BPS 产品类别: 其他生物试剂 规格: 20 μg 最后更新: 2024-12-5 货号: 70019 CAS 号: 参考报价: 6160 立即询价 电话咨询 [发表评论] [本类其他产品] [本类其他供应商] [收藏] 分享:微信...
Anti-APC(Activated protein C)??APC活化蛋白C抗体 抗原常规性能介绍 注意事项:本产品在存放时切记,不得长时间暴露在空气中,否则会降低本产品的含量,影响您的实验结果 产品说明:抗体即为免疫球蛋白,是改变了的球蛋白分子。由特抗原刺激产生,抗体的 产生是由于抗原侵入后引起各种免疫细胞相互作用,使B使淋巴 ...
英文名称:Activated Protein C (390 - 404), human 用途:科研 纯度:98% CAS编号: 146340-20-7 产地:中国 品牌:Chemstan 包装规格:1mg 货号:CS10489 是否进口:否 The peptide region containing residues 390-404 in Activated Protein C (APC) is essential for anticoagulant activity and is available for...
尽管初始数据充满希望,但是尚未证实重组人活化蛋白C(recombinant human activated protein C, rhAPC)能提高严重脓毒症或脓毒性休克患者的生存率,从而使得该药退市。rhAPC(也称为drotrecogin alfa)有促进纤维蛋白溶解和抑制血栓形成的作用。因为rhAPC...
北京伊莱瑞生物科技有限公司是专业的小鼠活化蛋白C(APC)检测试剂盒Mouse activated protein C,APC ELISA试剂盒厂家,为您提供价格优惠最佳解决方案,我们有小鼠活化蛋白C(APC)检测试剂盒Mouse activated protein C,APC ELISA试剂盒各种型号、资料、使用说明PDF文档,采购小
Deficient forms of the gene coding for activated protein C can contribute to disease states. One mutation can make cells unable to produce APC. Possessing a single copy of this gene can lead to the formation of blood clots in veins, known as venous thrombosis. Two deficient copies leads to ...