While second near-infrared (NIR-II) fluorescence imaging is a promising tool for real-time surveillance of surgical operations, the previously reported organic NIR-II luminescent materials for in vivo imaging ar
An activatable and tumor-targeting near-infrared (NIR) fluorescent probe CyAc-RGD was synthesized for the imaging of histone deacetylase 6 (HDAC6). The probe exhibited higher sensitivity and specificity for HDAC6 detection in cancer cells. Moreover, CyAc-RGD demonstrated good tumor-targeting ability...
ABSTRACT:Aclearelucidationofadisease-relatedviscositychangeinvivoissigni,cantyethighlychallengingaswell.Fluorescenceimaginginthesecondnear-infraredregion(NIR-II,1000−1700nm)hasgainedincreasingattentionforobservationinlivingorganisms,butaviscosity-activatable,uorescentprobeemittingatthisregionremainsavacancy.Herein,wereport...
Finally, this system, combined with the NIR probe, shows high specificity and sensitivity for detecting bladder cancer in isolated intact patient bladders.Similar content being viewed by others In situ self-assembly for cancer therapy and imaging Article 29 August 2023 Controlled sequential in situ...
To evaluate such in vivo dual-targeting abil- ity of FTRNPs, FL imaging and PAI were conducted on 4T1 tumor-bearing mice (n = 3). For FL imaging, Cy5.5- labeled-FTRNPs (10 mg/kg, Fe3O4) was systemic admin- istrated to demonstrate the active targeting (marked as FTRNPs)....
FAP Molecular imaging Liposomes Fluorescence-quenching 1. Introduction Two key factors that control the progression of cancer are the growth and survival of the tumor cells and their dissemination to distant host tissues, leading to metastasis. Although accumulating evidence reveal that the emergence of...
Activatable endoplasmic reticulum-targeted NIR fluorescent probe with a large Stokes shift for detecting and imaging chymotrypsin† Ting Lan,Qin-qin Tian,Ming-hua Li,Wei He Analyst Pub Date : 08/08/2022 00:00:00 , DOI:10.1039/D2AN01013E ...
Carbonized polymer dots are loaded into the nanosystem as an efficient bioimaging probe, due to the GE11 modification, the nanosystem can be a seeker to recognize and evaluate drug-resistance tumors by photoacoustic imaging. In the tumor-bearing mouse, the novel nanosystem firstly enhances the ...
A Probe for the Detection of Hypoxic Cancer Cells. ACS Sens. 2, 1139-1145 (2017). Luo, S. et al. A review of NIR dyes in cancer targeting and imaging. Biomaterials, 32, 7127-7138 (2011). Madala, H.R. et al. Brain- and brain tumor-penetrating disulfiram nanoparticles: Sequence ...
Park, K., et al., “New Generation of Multifunctional Nanoparticles for Cancer Imaging and Therapy”, Advanced Functional Materials 19, pp. 1553-1566 (2009). Kircher, M.F. et al., “A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor deli...