Action potential, the brief (about one-thousandth of a second) reversal of electric polarization of the membrane of a nerve cell (neuron) or muscle cell. In the neuron an action potential produces the nerve impulse, and in the muscle cell it produces the
The action potential is an explosive depolarization of the plasma membrane. It can be driven by the influx of calcium ions through voltage-gated calcium channels, as in the sea urchin egg, or sodium ions through voltage-gated sodium channels, as in human nerve cells. Action potentials travel ...
PDF Tools Share Abstract Introduction The aim of this article is to review the physiology of progesterone and focus on its physiological actions on tissues such as endometrium, uterus, mammary gland, cardiovascular system, central nervous system and bones. In the last decades, the interest of resea...
The thermodynamic theory of action potential propagation challenges the conventional understanding of the nerve signal as an exclusively electrical phenomenon. Often misunderstood as to its basic tenets and predictions, the thermodynamic theory is virtually ignored in mainstream neuroscience. Addressing a broad...
Action potential shapes and firing patterns differ widely among different types of neurons. One recognizable phenotype is that of fast-spiking neurons, which are capable of firing steadily at high frequencies and have narrow action potentials. This phenotype is typical of many interneurons and is asso...
It was found that when fibres were locally polarized to a level of -90 to -100 mV, and the external calcium concentrations was increased to 4 mM, the peak rate of rise and the overshoot of the action potential were maximal. Between 30 and 40 hrs following section of the motor nerve, ...
Although once considered to be biologically inert in human physiology in terms of production of NO activity [50], nitrite is now recognized as a storage pool for NO activity that is harnessed under hypoxia [51]. Resting plasma nitrite is at least hundreds times more abundant than steady state...
40Citations 4698Altmetric Metrics Abstract Considering the urgency of the ongoing COVID-19 pandemic, detection of new mutant strains and potential re-emergence of novel coronaviruses, repurposing of drugs such as ivermectin could be worthy of attention. This review article aims to discuss the probabl...
View PDFView articleView in ScopusGoogle Scholar Marathe et al., 2018 S.V. Marathe, P.L. D’Almeida, G. Virmani, P. Bathini, L. Alberi Effects of monoamines and antidepressants on astrocyte physiology: implications for monoamine hypothesis of depression J. Exp. Neurosci., 12 (2018) (...
Action Potential In the field of physiology, an action potential or AP occurs when the membrane potential of a specific cell at a particular location rises and falls with turbulence; this depolarization then causes adjacent cells to depolarize in the same manner. Action potentials take place in an...