Graph of an axon Action potential steps Practice Exams You are viewing quiz10 in chapter 2 of the course: Alberta Education Diploma - Biology 30: Exam Prep & Study Guide Course Practice 20chapters |176quizzes Explore our library of over 88,000 lessons ...
Average action potential and corresponding magnetic signals. (A) Result of triggering on nine consecutive APs from a trap lobe heated to 41 °C, then averaging the electric and magnetic data from a 4.5 s window around each trigger point. The average magnetic traces (bottom graph, opaque traces...
In order to examine the role that the endogenous opioid mechanism plays from a therapeutic perspective, we chose to use an adult-inducible Nav1.7 KO mouse that better models therapeutic block of Nav1.7 and avoids potential effects of removal of Nav1.7 during early development. We found that ...
As an initial step in characterizing the potential effect of nitrite on adhesion of circulating blood cells, we employed a microfluidic channel assay. An inflammatory mediator was used to activate confluent endothelial cells, and partially deoxygenated RBCs were passed through the channel. Adhesion was...
Abnormalities of ventricular action potential cause malignant cardiac arrhythmias and sudden cardiac death. Here, we aim to identify microRNAs that regulate the human cardiac action potential and ask whether their manipulation allows for therapeutic modu
Expression of Bcl-2, an anti-apoptotic regulator, is induced in the brain by ischemia consistent with the potential role of this protein as part of endogenous neuro-protective mechanism [30, 33]. Our results demonstrate that G-CSF can upregulate anti apoptotic protein Bcl2 (Fig. 5a and b)...
To investigate the interaction between OA and potential anti-obesity targets, the core targets identified by network pharmacology analysis were used as docking receptors, and OA was utilized as ligands for molecular docking via AutoDock. Initially, the 3D structure of OA was obtained in “mol2” ...
Conclusions This study has generated feasible hypotheses for the potential mechanism of action of Anle138b, which will enable the development of future molecular interventions aiming to reduce tau pathology in AD patients.Background Alzheimer’s disease (AD) is a chronic neurodegenerative disease charac...
Hyperpolarization-activated current Human Sinoatrial node Action potential clamp Heart rate β-adrenergic stimulation 1. Introduction The contribution of the hyperpolarization-activated ‘funny’ current (If) to the pacemaker activity of the mammalian sinoatrial node (SAN) has been, and still is, heavily...
Different methods, including novel Index of ideality correlation, were applied for the determination of the robustness of the model and its predictive potential. The Monte Carlo optimization process was capable of being an efficient in silico tool for building up a robust model of good statistical ...