Unlike BoNT/E, which distributes evenly within the cytosol by diffusion, BoNT/A protease is concentrated at the inner side of the plasma membrane. It appears that double-leucine motif is the determinant of such BoNT/A localization. The binding of BoNT/A near the synaptic membrane involves ...
The skeletal muscle progenitors’ proliferation and migration are crucial stages of myogenesis. Identifying drug candidates that contribute to myogenesis can have a positive impact on atrophying muscle. The purpose of the study is to synthesize theAntrodia cinnamomea(AC)-β-cyclodextrin (BCD) inclusion...