It was also desirable that, at a minimum, the drug candidate be active against all three encephalitic alphaviruses. However, a broader spectrum of activity to address multiple RNA virus threats would be highly desirable. To treat VEEV, the drug candidate would have to cross the blood–brain ...
Against this backdrop, governments will need to choose where and how to spend their COVID-19 emergency funds to realize maximum impact and value. Next, we explore five breakthrough ideas that could create impact across all three imperatives, with immediate and longer-term benefits. They ...
6 In addition to insulin, patients also require access to self-monitoring devices and strips, frequent monitoring of blood glucose control, and routine medical care to screen for and manage microvascular and macrovascular complications associated with T1DM.7 The costs of hypoglycemia and long-term ...
Beyond the SOLARIS study, Teva presented results from in vitro studies that evaluated TEV-'749 against the currently marketed intramuscular olanzapine long-acting injectable for the risk of PDSS, as well as Phase 1 data evaluating the pharmacokinetic characteristics of TEV-'749.1In the studies, TEV-...
we witnessed more deaths due to TB because of disruption or reallocation of health services, setting us back at least five to eight years in the global fight against TB. We think long-acting formulations could be a game-changer, whether it's for preventative therapy or treatment of disease....
Our research team has developed preparations based on natural raw materials with the addition of essential oils that act as a repellent against ticks. In addition to their pleasant scent, our preparations are environmentally friendly because they consist of natural ingredients. Abstract Background: ...
Yet the vaccine is not effective against genital herpes, let alone other HSV infections. Therefore, it is of great significance to develop new anti-HSV-1 drugs with lower toxicity by acting via a different mechanism compared to the nucleoside analogue. The issue of drug resistance should also ...
The UK Secretary of State for Health and Social Care, in an urgent plea during the autumn of 2020, cautioned young people against putting their grandmothers at risk upon returning home, as a surge in coronavirus cases was unequivocally linked to students being away from home for the first ...
Considering many TCM has the function of “clearing liver-fire”, it is therefore of great significance to develop the screening and evaluation of the efficacy of TCM against HSV-1. 1.2. Mechanism and Defects of Current Anti-HSV-1 Drugs There are many ways to treat a viral infection. On ...
accompanied with fever and inflammation; thus, among the compounds in the series 2-(4-methoxyphenyl)-1-[2-(morpholin-4-yl)ethyl]-1H-benzimidazole (2b) seems to be most powerful candidate for the treatment of a such disease, with dual activity against Pseudomona aeuroginosa ATCC and COX ...