B, basal surface of α-actinin-4–depleted cells stained for α-actinin-4, paxillin, and actin. C, graph of the mean average intensity ±95% confidence interval of actin along filaments. The mean intensity is significantly greater in α-actinin-4–depleted cells. D, graph of the mean ...
Actinin-4 is preferentially involved in circular ruffling and macropinocytosis in mouse macrophages: analysis by fluorescence ratio imaging Araki N,Hatae T,Yamada T,et al.Actinin-4 is preferentially involved in cellular ruffling and macropinocytosis in mouse macrophages: analysis by fluorescence... N ...
66009-4-PBS targets beta actin as part of a matched antibody pair: MP51048-2: 66009-2-PBS capture and 66009-4-PBS detection (validated in Cytometric bead array) Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, rea...
α-actinin 4 is a member of the spectrin family of actin-binding proteins, involved in the regulation of cell motility and adhesion. It forms an anti-parallel rod-shaped heterodimer with the N-terminal actin-binding domain (ABD) at two ends, which mediate cross-linking F-actin to form acti...
Alpha, beta and gamma actin isoforms have been identified, with alpha actin being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. In particular, smooth muscle actin is an alpha actin that is found in skeletal...
ACT 1,3,4,12 | Actin 1, 3, 4, 12+4;℃运输/+4℃储存分享给好友: 详细描述 目录号:CLAS16-3139 品牌:Cedarlane Laboratories 规格:100 µg 目录价:¥8311.00 市场价格:¥6815.02 会员价格:¥6648.80 数量: 购买发起团购 结束时间: 参加人数:人...
Our study identified α-actinin-4 as a novel NHERF1 interaction partner and provided new insights into the regulatory mechanism of the actin cytoskeleton by NHERF1. 展开 关键词: F-actin PDZ protein interaction stress fiber ubiquitination
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Alpha actinins (ACTNs) are known for their ability to modulate cytoskeletal organization and cell motility by cross-linking actin filaments. We show here that ACTN4 harbors a functional LXXLL receptor interaction motif, interacts with nuclear receptors in vitro and in mammalian cells, and potently ...