To date, three different actin-related proteins have been discovered in C. elegans: , ,and (for actin related proteins-1, 2, and 3) fall in the three distinct classes, showing ~50%, ~47%, and ~33% identity to actins respectively. These genes were first identified in random cDNA ...
验证数据库 ¥980.00元/format:100ul 目录号:IDS0011 库存:现货 规格 产品信息 Catalog No. IDS0011 Reactivity Human; Mouse; Rat; C.Elegans Applications WB; IHC-p Alternative Names Actin-1; act-1 Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.07% sodium azide. ...
In C. elegans, activation of Wnt signaling alters the activity of the TCF/LEF transcription factor, POP-1, through activation of the Wnt/-catenin or Wnt/-catenin asymmetry pathways. In this study, we have identified CACN-1 as a potential regulator of POP-1 in C. elegans larval ...
Genetic defects in beta-spectrin and tau sensitize C. elegans axons to movement-induced damage via torque-tension coupling. eLife 6, e20172 (2017). This paper reports an elegant combination of biophysical measurements and high-resolution microscopy in neurons with numerical simulations, showing how ...
Self-organization25 is a hallmark of actomyosin networks, with morphologically diverse examples such as the lamellipodia of crawling keratocytes26 and neutrophils27, the flowing cortex of C. elegans zygotes28, and dense actin networks of in vitro motility systems29. Drawing on continuum theories ...
elegans gene ced-9; see ced mutant. Bcl-3 (446aa) acts as an IκB homologue that interferes with NFκB signalling. Bcl-6 (706aa) is a transcriptional repressor. Bcl-2 homology domains Domains within the Bcl-2 family of proteins (BH1, BH2 etc.) that are involved in protein-protein ...
A biomimetic synthesis of ligantrol, a linear polyoxygenated diterpene from Liatris elegans, was carried out using an epoxide intermediate (Scheme 52) 〈78CPB3416〉. Cyclizations via intramolecular Michael additions of ε-hydroxy α,β-unsaturated systems have proved useful in constructing ...
Erratum: Adhesive L1CAM-Robo Signaling Aligns Growth Cone F-Actin Dynamics to Promote Axon-Dendrite Fasciculation in C. elegans (Developmental Cell (2019) ... Neuron connectivity depends on growth cones that navigate axons through the developing brain. Growth cones protrude and retract actin-rich st...
In all cases there are thin filaments which are ... J Hanson,J Lowy - 《Journal of Molecular Biology》 被引量: 674发表: 1963年 The structure of nonvertebrate actin: Implications for the ATP hydrolytic mechanism The structures of Saccharomyces cerevisiae, Dictyostelium, and Caenorhabditis elegans ...
Recent work has shown that non-neuronal tissues in C. elegans experience actin filament destabilization and a decline in cytoskeletal integrity with age5. However, little is known about actin dynamics in the brains of aging organisms. Using the Drosophila model, we examined actin in the brains of...