et al. Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis. Nat Cell Biol 25, 404–414 (2023). https://doi.org/10.1038/s41556-023-01091-2 Download citation Received16 March 2022 Accepted12 January 2023 Published06 February 2023 Issue DateMarch 2023 DOIhttps://doi.org...
2023年2月6日,来自德克萨斯大学MD安德森癌症中心的甘波谊和陈俊杰教授团队在Nature Cell Biology杂志发表了题为“Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis”的研究。该研究详细介绍了一种以前无法解释的细胞死亡类型——Disulfidptosis(二硫死亡或双硫死亡),可能为新的癌症治疗策略打开...
they undergo NADPH depletion and an aberrant accumulation of intracellular cystine and other disulfide molecules (e.g., actin cytoskeleton proteins). This leads to disulfide stress, alterations in protein function, the collapse of the actin network, ...
28. Recently, LPL was shown to enable the plasticity of invadopodial and filopodial structures, which is potentially critical for the rapid remodeling of the cytoskeleton in response to stimuli29.
Moreover, the less-studied aspects of this newly discovered cell death process are highlighted to stimulate further investigations in this field. Graphical AbstractSimilar content being viewed by others Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis Article 06 February 2023 ...
2023年2月6日,来自德克萨斯大学MD安德森癌症中心的甘波谊和陈俊杰教授团队在Nature Cell Biology杂志发表了题为“Actin cytoskeleton vulnerability to disulfide stress mediates disulfidptosis”的研究。该研究详细介绍了一种以前无法解释的细胞死亡类型——Disulfidptosis(二硫死亡或双硫死亡),可能为新的癌症治疗策略打开...