Vav1 Phosphorylation Is Induced by β2 Integrin Engagement on Natural Killer Cells Upstream of Actin Cytoskeleton and Lipid Raft Reorganization The guanine nucleotide exchange factor Vav1 regulates actin polymerization and contributes to cytotoxicity by natural killer (NK) cells. An open question i......
The actin cytoskeleton is composed of a highly dynamic network of filamentous proteins, yet the molecular mechanism that regulates its organization and remodeling remains elusive. In this study, Na(+)/H(+) exchanger regulatory factor (NHERF)-1 loss-of-function and gain-of-function experiments rev...
英文: A lot of studies showed that ADF/cofilin is essential to the function and organization of actin cytoskeleton which is necessary to cell elongation and tip growth. 中文: 许多研究表明,ADF/cofiun(actin depolymerizing factor/cofilin)对肌动蛋白骨架的组装和功能至关重要,而肌动蛋白骨架对细胞伸长和...
All the results above show that the dynamic organization of the actin cytoskeleton are critical in the cell polarity formation and germination of pollen protoplast, and that the reorganization of actin cytoskeleton is mainly due to the rearrangement of actin filament arrays. 展开 关键词: 肌动蛋白...
We have examined effects of arginine starvation on cell motility, adhesion and invasiveness as well as on actin cytoskeleton organization of human glioblastoma cells. We observed for the first time that arginine, but not lysine, starvation affected cell morphology, significantly inhibited their motility...
Coupled with work previous work by Mori et al.37., our data describe a mechanism linking immune-induced changes in actin cytoskeleton organization to the modulation of stomatal closure. Taken together, these data provide evidence linking actin to additional key signaling processes mediated by CPK, ...
Effects of Microinjection of GST Fusion Proteins and Antibodies on Cytoskeleton Organization and DNA Synthesis As seen in Fig. 2,C and D, electroporation of GST-Crk-SH2 into the cells almost completely inhibited the endogenous CrkII SH2 domain binding to p130cas, whereas GST-Crk-(N)SH3 was...
Article: Gliotoxin from Aspergillus fumigatus affects phagocytosis and the organization of the actin cytoskeleton by distinct signalling pathways i
The F-actin cytoskeleton is the main driving force of dendritic spine remodeling and sustains synaptic plasticity. It is therefore essential to understand how changes in synaptic transmission can regulate the organization and dynamics of actin binding proteins (ABPs). In this review, we will provide...
Organization of actin cytoskeleton during early endothelial regeneration in vitro The pattern of early after an experimental 'wound' and the organization of in stationary and moving cultured endothelial cells have been studied by means o... G Gabbiani,F Gabbiani,RL Heimark,... - 《Journal of Cel...