Actin and myosin disruptors also affect intercellular transport in some species, implying that actomyosin contraction may regulate transport either at the plasmodesma neck or by altering bulk flow from cell to cell. These findings suggest that, together with other contractile proteins, actin and ...
What Actin and Myosin Do in the Nucleus: New Functions of the Well-Known Proteins Abstract
Here we show that in myosin V (myo52 myo51) null cells, actin cables are curled, bundled, and fail to extend into the cell interior. They also exhibit reduced retrograde flow, suggesting that formin-mediated actin assembly is impaired. Myo52 may contribute to actin cable organization by ...
Together they form two globular heads, which give rise to the crossbridge in muscle and a coiled-coil rod, which forms the shaft of the thick filament. The isolated head fragment, subfragment-1 (S1), contains the ATPase and actin-binding activities of myosin (Fig. 1). Although S1 seems...
The actomyosin network that forms around the disassembling nuclear envelope in human mitotic cells16 is located on the cytoplasmic side of the nuclear envelope16 and requires nm-myosin II activity to move the chromosomes16. Despite these mechanistic differences, the network in mitotic cells was ...
Constriction of the cytokinetic ring, a circular structure of actin filaments, is an essential step during cell division. Mechanical forces driving the constriction are attributed to myosin motor proteins, which slide actin filaments along each other. Ho
two daughter cells to separate). Such assemblies of actin and myosin are also found in development near the apical surface of epithelial cells where they play a role in folding of epithelial sheets and inmesenchymewhere they can form stress fibres which allow the cells to exerttensionon theECM...
The actin- and myosin-binding protein, caldesmon (CaD) is an essential component of the cytoskeleton in smooth muscle and non-muscle cells and is involved ... T Mirzapoiazova,IA Kolosova,L Romer,... - 《Journal of Cellular Physiology》 被引量: 100发表: 2005年 The Actin Cytoskeleton as...
the formation of these structures. For example, nucleating and capping proteins regulate the polymerization of monomeric actin into filamentous actin (F-actin). This polymerization process can generate protrusive forces within the cell.Crosslinking proteinsbind these actin filaments together to form ...
Troponin is essential in Ca(2+) regulation of skeletal and cardiac muscle contraction. It consists of three subunits (TnT, TnC and TnI) and, together with ... Solchi Takeda,A Yamashita,K Maeda,... - 《Nature》 被引量: 1080发表: 2003年 A structural state of the myosin V motor without...