It carries a risk of serious infections, haematological disorders (neutropenia, thrombocytopenia), gastrointestinal bleeding, hepatic disorders, and systemic and local reactions during the infusion; (5) the adverse effects of long-term tocilizumab therapy are unknown, particularly the risk of cancer; (...
What is Actemra infusion for? Actemra infusion may be used to treat several different conditions that have inflammation as a common characteristic, such as: Rheumatoid Arthritis Giant Cell Arteritis Systemic Sclerosis-Associated Interstitial Lung Disease Polyarticular Juvenile Idiopathic Arthritis Systemic...
Hypersensitivity reactions, including anaphylaxis, have been reported in association with ACTEMRA and anaphylactic events with a fatal outcome have been reported with intravenous infusion of ACTEMRA. ACTEMRA for intravenous use should only be infused by a healthcare professional with appropriate medical sup...
Serious allergic reactions, including death, can happen with ACTEMRA. These reactions can happen with any infusion or injection of ACTEMRA, even if they did not occur with an earlier infusion or injection. Tell your healthcare provider before your next dose if you had hives, rash or flushing...
ACTEMRA can be given in two ways for PJIA: intravenous (IV) infusion or subcutaneous (SC) injection. Learn about treatment options » See the results See how other children with PJIA responded to ACTEMRA in a clinical trial. Results may vary. ...
ACTEMRA can be given in two ways for SJIA: intravenous (IV) infusion or subcutaneous (SC) injection. Learn about treatment options » See the results See how other children with SJIA responded to ACTEMRA in a clinical trial. Results may vary. ...
There is sufficient evidence to make it a first-line biologic therapy in rheumatoid arthritis, systemic juvenile inflammatory arthritis, and Castleman's disease. Its efficacy as monotherapy makes it the treatment of choice for those with rheumatoid arthritis who cannot take methotrexate. It also has ...
The side effects of getting any medicine by vein may include brief pain, bleeding, bruising of the skin, soreness, swelling, and possible infection at the infusion site. Patients should not receive ACTEMRA if they are allergic to tocilizumab or if they have had a bad reaction to ACTEMRA prev...
2 DOSAGE AND ADMINISTRATION 2.1 Rheumatoid Arthritis ACTEMRA may be used as monotherapy or concomitantly with methotrexate or other non-biologic DMARDs as an intravenous infusion or as a subcutaneous injection. Recommended Intravenous (IV) Dosage Regimen: The recommended dosage of ACTEMRA for adult ...
Indicated for adults with moderate-to-severe active rheumatoid arthritis with inadequate response to 1 or more disease modifying antirheumatic drugs (DMARDs) May use alone or in combination with methotrexate or other DMARDs IV infusion 4 mg/kg IV q4Weeks initially; may increase to 8 mg/kg q4...