Usual Adult Dose of Actemra for Rheumatoid Arthritis:IV: 4 mg/kg IV as a 60-minute single drip infusion once every 4 weeks, followed by an increase to 8 mg/kg IV given once every 4 weeks as a 60-minute single drip infusion based on clinical response, doses exceeding 800 mg per in...
It carries a risk of serious infections, haematological disorders (neutropenia, thrombocytopenia), gastrointestinal bleeding, hepatic disorders, and systemic and local reactions during the infusion; (5) the adverse effects of long-term tocilizumab therapy are unknown, particularly the risk of cancer; (...
ACTEMRA may be used as an intravenous infusion or as a subcutaneous injection alone or in combination with methotrexate. Do not change a dose based solely on a single visit body weight measurement, as weight may fluctuate. Recommended Intravenous Dosage Regimen The recommended dose of ACTEMRA for ...
Actemra is supplied as a sterile, preservative-free solution for intravenous (IV) infusion at a concentration of 20 mg/mL. Actemra is a colorless to pale yellow liquid, with a pH of about 6.5. Single-use vials are available containing 80 mg/4 mL, 200 mg/10 mL, or 400 mg/20 mL of...
ACTEMRA can be given in two ways for SJIA: intravenous (IV) infusion or subcutaneous (SC) injection. Learn about treatment options » See the results See how other children with SJIA responded to ACTEMRA in a clinical trial. Results may vary. Learn more » Coverage and patient assistan...
ACTEMRA is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs). ACTEMRA is indicated for the treatment of giant cell arteritis (GCA) in adult...
ACTEMRA can be given in two ways for PJIA: intravenous (IV) infusion or subcutaneous (SC) injection. Learn about treatment options » See the results See how other children with PJIA responded to ACTEMRA in a clinical trial. Results may vary. ...
Changes in Blood Test Results Your healthcare provider should do blood tests before you start receiving ACTEMRA. If you have rheumatoid arthritis (RA) or giant cell arteritis (GCA), or systemic sclerosis-interstitial lung disease (SSc-ILD) your healthcare provider should do blood tests 4 to 8...
2 DOSAGE AND ADMINISTRATION 2.1 Rheumatoid Arthritis ACTEMRA may be used as monotherapy or concomitantly with methotrexate or other non-biologic DMARDs as an intravenous infusion or as a subcutaneous injection. Recommended Intravenous (IV) Dosage Regimen: The recommended dosage of ACTEMRA for adult ...
Tocilizumab has primarily been employed in the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a rare form of aggressive autoimmune arthritis in children. It is usually administered as an intravenous infusion or subcutaneous injection (Source). ...