Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian canc- er cells [ J ] BMC Cancer, 2015,15 ( 1 ) :290.Orellana R., Kato S., Erices R., Bravo M. L., Gonzalez P., Oliva B., et al. (2015...
A delicate equilibrium of WNT agonists and antagonists in the intestinal stem cell (ISC) niche is critical to maintaining the ISC compartment, as it accommodates the rapid renewal of the gut lining. Disruption of this balance by mutations in the tumour suppressor gene APC, which are found in ...
Distinct myeloid cell populations, such as tumor- associated macrophages (22,23), Tie2- expressing monocytes (24) and myeloid- derived suppressor cells (25), have been implicated as key players in the angio- genic process. Although initially these monocytic subpopulations were de- scribed as ...
leprae Hsp65 elutes as proteins of masses in the range from 20 000 Da to 23 500 Da. These sequences confirm the identity of the recombinant protein which presented a total molecular mass of 56 891.9 Da, consisting of 541 amino acid residues (data not shown). 2.2. Preparation of full-...
You're also entitled to a free report directly from the credit reporting bureaus if you've recently been denied credit, have been turned down for a job, are on public assistance, or have reason to suspect that you're a victim of credit fraud or identity theft. ...
Here we reveal another property of actin that is exploited by a virus; actin can act as a cofactor to stimulate a virus-coded proteinase. Throughout an adenovirus infection, the actin, cytokeratin, tubulin, and vimentin networks that make up the cytoskeleton of the cell undergo dramatic changes...
Following the death, the Department of Justice (DOJ) immediately deemed it a suicide, denied the medical examiner access to the cell where Kenneth Trentadue was killed, ordered the cell cleaned and painted, and repeatedly asked both the medical examiner and Kenneth Trentadue’s family to authorize...
Targeting KDM6B by using a specific inhibitor reduces the expression of CSCs markers namely SOX-2, SOX-9 and CD44 in matrix detached cancer cells. We found that KDM6B occupies the promoter region of both SOX-2 and CD44 and thereby regulate their expression. Surprisingly, we also noticed that...
In C. elegans, dpl-1 and efl-1 normally inhibit, whereas RTK/Ras signaling normally promotes, vulval cell-fate specification. Therefore, dpl-1 and efl-1 antagonize RTK/Ras pathway function in vulval development. As discussed above, the function of DPL-1 and EFL-1 as transcriptional ...
5. The nucleic acid fragments typically exhibit at least eighty percent sequence identity to the nucleic acid sequence of FIG. 5. The invention also provides isolated cell lines containing the nucleic acid fragments discussed supra. The cell lines usually express an ACT-4 receptor polypeptide on ...