It promotesadipocyte differentiation, fatty acid catabolism, and insulin sensitivity, and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. In this context, adiponectin is an antiinflammatory agent, but it...
运输条件:美国大陆的室温;其他地方可能有所不同。 产品活性:Adiponectin/Acrp30 蛋白, Mouse (HEK293, His)是脂肪细胞分泌的最丰富的肽,其减少在肥胖相关疾病,包括胰岛素抵抗/ 2型糖尿病和心血管疾病中起核心作用。 生物活性:通过抑制大鼠肝细胞产生葡萄糖的能力来衡量。该作用的IC50为≤1.304 μg/mL,对应的比活...
Low serum level ofadiponectin is found in obesity, type 2 diabetes and those with coronary artery disease.Therefore, adiponectin serves as an important clinical biomarker for metabolic syndromes. Verified Reactivity :Human Antibody Type :Monoclonal Host Species :Mouse Immunogen :Recombinant human ...
Adiponectin, also known as Acrp30, is an adipocyte-derived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation. It promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity, and is negatively correlated with obesity, type 2 diabetes, and athe...
and obesity. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); cardiovascular system disease (multiple); non-alcoholic fatty liver disease; primary open angle glaucoma; and type 2 diabetes mellitus. Orthologous to human ADIPOQ (adiponectin, C1Q and collage...
Adiponectin has been shown to play a role in various physiological processes including homeostasis and obesity. Decreased levels of adiponectin are associated with obese individuals as well as insulin resistance and hyperinsulinemia (type 2 diabetes). In mice adiponectin has been shown to improve ...
Adiponectin/Acrp30 Protein, Mouse (227a.a)能够抑制内皮炎症反应和血管平滑肌细胞增值,还能抑制巨噬细胞向泡沫细胞转化。 Synonyms:rMuAdiponectin; Acrp-30; GBP-28; Apm-1; Acrp 30; Acrp30 Species:Mouse Source:E. coli Biological Activity:The ED50is <5 μg/mL as measured by M1 cells, correspondin...
Adiponectin circulates in the plasma. Decreased levels of Adiponectin are associated with insulin resistance and hyperinsulinemia, as seen in people with obesity insulin resistance, and diabetes type 2, whose plasma levels of adiponectin are reduced.The modular structure of Acrp30 is comprised of N-...
Adiponectin, also known as Acrp30, is an adipocyte-derived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation. It promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity, and is negatively correlated with obesity, type 2 diabetes, and athe...
Here we investigated the biological functions of adiponectin/ACRP30, a fat-derived hormone, by disrupting the gene that encodes it in mice. Adiponectin/ACRP30-knockout (KO) mice showed delayed clearance of free fatty acid in plasma, low levels of fatty-a