malonyl-S-ACP:biotin-protein carboxyltransferase 2.1.3.10doi:10.1007/978-3-642-36240-8_31EC number 2.1.3.10 Systematic name malonyl-[acyl-carrier protein]:biotinyl-[protein] carboxytransferase Recommended name malonyl-S-ACP:biotin-protein...
malonyl-CoA-ACP transferase(MT) 丙二酰CoA-ACP 转移酶 β-ketoacyl-ACP reductase(KR) β-酮酰-ACP 还原酶 β-hydroxyacyl-ACP dehydratase(HD) β-羟酰-ACP 脱水酶 enoyl-ACP reductase(ER) 烯酰-ACP 还原酶 在FAS I中,AT和MT由另一个酶取代:Malonyl/acetyl-...
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The malonyl transferase activity of type II polyketide synthase acyl carrier proteins. Chem Biol. 2006;13(6):587–96. Article CAS PubMed Google Scholar Misra A, Sharma SK, Surolia N, Surolia A. Self-acylation properties of type II fatty acid biosynthesis acyl carrier protein. Chem Biol. ...
ACP的结构类似辅酶A,都具有4' 酸泛酸硫氢乙胺 -磷.
Purification of a malonyltransferase from Streptomyces coelicolor A3(2) and analysis of its genetic determinant. Streptomyces coelicolor A3(2) synthesizes each half molecule of the dimeric polyketide antibiotic actinorhodin (Act) from one acetyl and seven malonyl buil... W,P,Revill,... - 《Journa...
Each domain is abbreviated as follows: MAT malonyl-ACP transacylase, KS ketosynthase, KR ketoreductase, DH dehydratase, ER enoylreductase, and AT acyl transferase. AcpP-DH structures depicted in bottom two quadrants are AcpP–FabZ (PDB: 6N3P), AcpP–FabA (PDB: 4KEH). b, c Cartoon ...
These products could be generated by either direct PhaG thioesterase activity on medium-chain acyl-ACPs or by CoA thioesterase activity on stranded pools of 3-hydoxyacyl-CoAs made via PhaG transferase activity. ***P = 0.0005 was analyzed based on student two-tailed t test assuming unequal...
The complex is composed of four proteins: biotin carboxyl carrier protein (BCCP) encoded within accB; biotin carboxylase encoded within accC; and the carboxyltransferase subunits encoded within accA and accD. The second enzyme of the pathway, malonyl-CoA:ACP transacylase encoded within the ...
These genes encode the malonyl-CoA:ACP transferase (MCT1) and the 3-oxoacyl-ACP reductase (OAR1) and are both required for mtFAS activity (Figure S2A) (Hiltunen et al., 2009). As such, these mutant strains are unable to synthesize ACP-bound acyl chains. Interestingly, the Sdh6 LYR ...