In an ackA - pta strain, the flux to acetate was decreased dramatically, whereas flux to lactate was increased significantly when compared with its parent strain; the fluxes to pyruvate and ethanol also increased slightly. In addition, pyruvate was excreted. A strain carrying the nuo mutati...
www.nature.com/scientificreports OPEN Acetate fluxes in Escherichia coli are determined by the thermodynamic control of the Pta-AckA pathway received: 11 October 2016 accepted: 28 December 2016 Published: 10 February 2017 Brice Enjalbert*, Pierre Millard*, Mickael Dinclaux, Jean-Charles ...
The Pta–AckA pathway controlling acetyl phosphate levels and the phosphorylation state of the DegU orphan response regulator both play a role in regulatin... (2008) The Pta-AckA pathway controlling acetyl phosphate levels and the phosphorylation state of the DegU orphan response regulator both ...
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Down Regulation of ackA-pta Pathway in Escherichia coli BL21 (DE3): A Step Toward Optimized Recombinant Protein Expression System.doi:10.5812/jjm.8990AcetateAntisenseRNADown-RegulationEscherichiacoliBackground: One of the most important problems in production of recombinant protein is to attain over-...
The Pta-AckA pathway controlling acetyl phosphate levels and the phosphorylation state of the DegU orphan response regulator both play a role in regulating Listeria monocytogenes motility and chemotaxis. Mol Microbiol. 2008; 70 (6):1342–1357....
Here, we found that ackA and pta contribute to fosfomycin activity against E. coli. ackA and pta mutant E. coli had reduced fosfomycin uptake capacity and became less sensitive to this drug. In addition, ackA and pta mutants had decreased expression of glpT that encodes one of the ...
Mizrahi I, Biran D, Ron EZ. Involvement of the Pta-AckA pathway in protein folding and aggregation. Res Microbiol. 2009; 160 :80–84.Mizrahi I, Biran D, Ron EZ (2009) Involvement of the Pta-AckA pathway in protein folding and aggregation. Res Microbiol 160:80–84...
Transcriptomic Studies of an Amorphadiene Producing E. Coli Strain in an Acka/Pta/Poxb Deletion BackgroundThe engineered production of the precursors to the anti-malarial drug, artemisinin, via the exogenous mevalonate pathway in branches from the central carbon metabolic pathway at acetyl Co-A. ...