Current guidelines recommend Na(+)-based alkali for CKD with metabolic acidosis and plasma total CO2 (PTCO2) < 22 mM. Because diets in industrialized societies are typically acid-producing, we compared base-producing fruits and vegetables with oral NaHCO3 (HCO3) regarding the primary outcome of ...
[HCO3].3-5It follows that over the course of progressive GFR decline, metabolic acidosis is a comparatively late complication of CKD. When defined as plasma [HCO3] < 22 mEq/L, the level at which current Kidney Disease: Improving Global Outcomes (KDIGO) guidelines recommend treatment of ...
By multivariate logistic regression analysis, the main characteristics of patients with adequate control of MA were: age (OR = 1.03; 95% CI 1.01 – 1.05), baseline GFR (OR = 1.07; 1.02 – 1.12), and treatment with proton-pump inhibitors (OR = 1.61; 95% CI 1.06 – 2.44). Patients ...
screening methods useful in the identification of a suitable inhibitor of a bacterial α-amylase and/or α-glucosidase for the treatment of acidosis in a ruminant; a process for improving ruminant milk quality and/or quantity which comprises treatment of a ruminant with an effective amount of an...
OBJECTIVE: To present a case report of a pregnant woman who presented with diabetic ketoacidosis, treatment and evolution. Given the low frequency of the pathology, it is interesting to report and review the current literature. CLINICAL CASE: A 32-year-old woman, with the diagnosis of ...
In the presence of severe metabolic acidosis and even MODS, multiple supportive cares, including VV-ECMO, CRRT, TTM, etc., should be quickly considered as treatment strate- gies for DCA since full and rapid recovery is possible. As a matter of fact, strict cooperation of emergence medical ...
[14] Mariano F, Benzi L, Cecchetti P, et al. Efficacy of continuous venovenous haemofiltration (CVVH) in the treatment of severe phenformin-induced lactic acidosis[J]. Nephrol Dial Transplant, 1998, 13(4):1012-1015. [15] Chodock R, Mylonakis E, Shemin D, et al. Survival of a hum...
In sharp contrast to the responsive MC38wt and CT26wt cancer cells, no acidosis- induced increase in cell surface PD-L1 expression was observed upon IFN-γ treatment in B16-F10wt and 4 T1wt cancer cells (Fig. 2G, H). Moreover, we screened five human cancer cell lines, ...
Conclusions The results of this survey indicate that the decisions whether to use base for the treatment of acute severe metabolic acidosis, and under which circumstances, vary among physicians, and indicate the need for further studies to develop evidence-based guidelines for therapy. 展开 ...
of cleaved Caspase-3 (Figure 2F,G) and PI staining revealed a decreased proportion of PI-positive cells in the pH 6.2 + Mel group (Figure 2H,I). These findings indicate that melatonin restored TFEB nuclear translocation and autophagy and alleviated neuronal damage caused by acid treatment. ...