Attempts to study nucleic acid synthesis in the blood-stream form of Trypanosoma vivaxattempts to study nucleic acid synthesis in the blood-stream form. of trypanosoma vivaxdoi:10.1016/0035-9203(66)90195-7Newton B.A.Elsevier LtdTransactions of the Royal Society of Tropical Medicine & Hygiene...
The nature and properties of sialic acid, for which studies were ; recently made in the field of serum glycoprotein physiopathology, are discussed. ; It is shown that this substance undergoes a remarkable increase in the blood of ; the whole-body irradiated rabbit. This is probably caused by...
The stability of blood fatty acids during storage and potential mechanisms of degradation: A review Adam H.Metherel,Ken D.Stark, inProstaglandins, Leukotrienes and Essential Fatty Acids, 2016 Abstract Fatty acids in blood samples, particularlypolyunsaturated fatty acids(PUFAs), are susceptible to degr...
Recently it was found that normal adults excrete pipecolic acid primarily as the D-enantiomer even though it is present in the blood stream mainly as the L-enantiomer (i.e. > 98% L). This study of pipecolic acid stereochemistry was extended to subjects with peroxisomal deficiencies since they...
. Metastatic cancer cells often express a high density of sialic acid-rich glycoproteins. This overexpression of sialic acid on surfaces creates a negative charge on cell membranes. This creates repulsion between cells (cell opposition) and helps these late-stage cancer cells enter the blood stream...
Hence, when this function of the carbohydrates becomes impaired, these acids, Oxybutyric acid, Diacetic acid and Acetone, fail to be neutralized and are consequently absorbed into the blood stream, giving rise to a form of intoxication known as acidosis. ...
A method of treating a person for sickle cell anemia including administering to the patient's blood a therapeutically effective dosage of ethacrynic acid. The dosage may be administered to blood removed from the patient which blood after addition of the compound is restored to the patient or by...
Endothelial dysfunction and senescence accompany T2D and are likely the result of an overabundance of endothelium damaging factors in the blood stream, including pro-oxidant molecules, glucose and lipids or FFAs [52, 53]. Importantly, inducing senescence in ECs strongly up-regulates the expression ...
While the bulky aggregates continuously trap into the tumor interstitium, the intact nanoprobes in normal brain tissue can be transported back into the blood stream in a timely manner. Experimental results show that physiological acidity triggers nanoparticle assembly by forming 3D spherical nanoclusters...
and degradation in theblood streamlimit their application. These challenges can be overcome by the use of a suitablenucleic acid deliverysystem (in the form of nano- or microcariers).Nucleic acid deliverysystems are of two categories, namely viral and nonviral systems. This chapter is a concise...