Finally, the hydroxynitrile derivative is subjected to hydrolysis and simultaneously removal of protecting group by e.g. treating with HCl to provide the compound expressed by the formula.KAMIJO TETSUKIYOHARADA HIROSHITSUBAKI ATSUSHIYAMAGUCHI TOSHIAKI...
Glycolic acid is made industrially by hydrolysis of monochloroacetic acid, by electrolytic reduction of oxalic acid, or by condensing carbon monoxide with formaldehyde under pressure in the presence of acid catalysts. Glycolic acid is used in the textile industry (in dyeing), in the leather industry...
The present invention is directed to a process for improving the specific activity of a dehydrated enzyme catalyst having nitrilase activity for hydrolysis of glycolonitrile to glyc
(COOR)2 in the presence of an acyl peroxide, converting the resulting ester (CH3)2 CH-CH2-CH(CO-CH3)-CH(COOR)2 into the compound (CH3)2CH-CH2-CH(CO-CH3)CH2 -COOR, for example, by hydrolysis with methanolic KOH followed by acidification and esterification with ethanol, and finally, ...
After hydrolysis and desulphurisation the desired intermediate (S)-2-hydroxy-2-methylbutyric acid (10) was obtained with 99 % ee. Interestingly, when applying (R)-selective HNL from Prunus amygdalus again the (S)-cyanohydrin 5 was formed (62 % ee). The absolute configuration of 5 ...
comprising reacting an α-hydroxynitrile represented by formula (I): ##STR2## wherein R is as defined above, or a mixture of an aldehyde represented by formula (II): R--CHO (II) wherein R is as defined above, and hydrogen cyanide with a microorganism capable of producing such an amide...
A process for the production of alpha -hydroxy acids or alpha -hydroxyamides in which an alpha -hydroxynitrile compound or a mixture consisting of an aldehyde and prussic acid, which corresponds to the nitrile compound, is allowed to undergo a microbial reaction to produce the corresponding alpha...
Finally, the hydroxynitrile derivative is subjected to hydrolysis and simultaneously removal of protecting group by e.g. treating with HCl to provide the compound expressed by the formula.上條 哲聖原田 弘椿敦山口 敏章伊與部 亮飯塚 欣二
Finally, the hydroxynitrile derivative is subjected to hydrolysis and simultaneously removal of protecting group by e.g. treating with HCl to provide the compound expressed by the formula.伊與部 亮原田 弘木曾 良明山口 敏章飯塚 欣二上條 哲聖...
A process for the production of &agr;-hydroxy acids or &agr;- hydroxyamides in which an &agr;-hydroxynitrile compound or a mixture consisting of an aldehyde and prussic acid, which corresponds to the nitrile compound, is allowed to undergo a microbial reaction to produce the corresponding &...