24. Enolate Chemistry: Reactions at the Alpha-Carbon Video LessonsWorksheetPractice AI Tutor Topic summary Created using AI Alphahalogenationinvolves electrophilic alpha substitutions that can occur via acid orbasecatalyzed mechanisms, yielding different products. The acid catalyze...
Being harder to control, the acid-catalyzed aldol tends to get less use than the base-catalyzed version. [Note 5] Still, it’s instructive because it actually highlightsthree key waysthat acid can catalyze reactions, which roughly highlights the three stages of this reaction. In the first stag...
As in the case of CylK, whether BrtB-catalyzed esterification occurs via a SN1 or SN2 mechanism is yet to be found11,12; we will focus future efforts on its structural and mechanistic characterization. Our discovery of a O–C bond forming reaction paved the way for identifying a series ...
are obtained by the dehydrohalogenation of the corresponding α,#- dihalopropionic acid derivatives of the formula using alkali-metal monohydrogen phosphates as catalysts, the process being effected by heating an aqueous mixture of the propionic acid derivative and of the alkali-metal hydrogen phosphat...
Stille JK, Tanaka M (1987) Intramolecular palladium-catalyzed cyclizations of esters containing vinyl triflate and vinylstannane groups at the termini: synthesis of large-ring lactones. J Am Chem Soc 109: 3785–3786 CAS Google Scholar Pattenden G, Thom SM (1993) Polyene macrolactam construction...
Consideration must be given when the 4-carboxylic acid group is esterified or transformed since the 3,4-double bond is especially prone to base-catalyzed isomerization 〈86JOC4723, 92JOC4027〉. Other factors to be considered in choosing protecting groups include formation and removal...
A new protecting group for aspartic acid that minimizes piperidine-catalyzed aspartimide formation in Fmoc solid phase peptide synthesis. Tetrahedron Lett. 37, 4243–4246 (1996). Article Google Scholar Behrendt, R., Huber, S., Martí, R. & White, P. New t -butyl based aspartate protecting...
Benzoic acid is produced commercially by partial oxidation of toluene with oxygen. The process is catalyzed by cobalt or manganese naphthenates. The process uses cheap raw materials, proceeds in high yield, and is considered environmentally green. ...
Substituted 2-aminothiazole derivatives were obtained as a result of N-methylimidazole catalyzed cyclization of α-halo ketone carbonyls with ammonium thio... HM Meshram,PB Thakur,BM Babu,... - 《Tetrahedron Letters》 被引量: 8发表: 2012年 A new and efficient method for the synthesis of α,...
Merbouh, N., et al., “4-AcNH-Tempo-Catalyzed Oxidation of Aldoses to Aldaric Acids Using Chlorine or Bromine as Terminal Oxidants,” 2002, J Carbohydrate Chem, 21/1&2: 65-77. International Search Report issued in PCT/US2010/060143 dated Apr. 5, 2011, 6 pages. Written Opinion ...