Achalasia was classified into types I (25%), II (65%), and III (9.7%). TBE height at 5 minutes was higher for I (median 8 cm; interquartile range 6–12) and II (8 cm; 8–11) than for III (1 cm; 0–7). TBE width at 5 minutes was widest (3 cm; 2–4), ...
57, 58, 59 However, a substantial drawback of its use is the occurrence of side-effects such as hypotension, headache, and dizziness in up to 30% of patients.57, 58, 59 Moreover, drug tolerance develops with time.62 A more widely used pharmacological treatment is botulinum toxin A, a ...
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POEM has been used for all types of esophageal motility disorders, including, but not restricted to, advanced sigmoid achalasia and spastic motility disorders of the esophagus [50, 51]. POEM has even been performed successfully on refractory cases of achalasia following previous balloon dilation or ...
Importantly, participants emphasised the significance of making this co-designed intervention available at the early stages of their diagnosis and treatment pathway. The chronic nature of their condition highlights the persistent challenges faced by people living with achalasia and the ongoing need for ...
development of a minimally invasive technique for performing a long oesophageal myotomy, the per-oral endoscopic myotomy (POEM). Optimal management is to render treatment in a phenotype-specific manner; that is, POEM calibrated to patient-specific physiology for spastic achalasia and the spastic disord...
there is a dilated esophagus or sigmoid tortuosity and sometimes, in advanced cases, massive dilatation of the esophageal body that have implications for treatment [1,5]. The typical finding in achalasia is the presence of smooth tapering of the lower esophagus leading to a closed LES, resembling...
What are Different Types of Swallowing Problems? What is Deglutition? What is a Tracheoesophageal Fistula? What is an Esophageal Manometry? What is Esophagogastroduodenoscopy? Discussion Comments WiseGeek, in your inbox Our latest articles, guides, and more, delivered daily. ...
However, while it is clear that EAC originates from glandular cells near the stomach, BE consists of many cell types, and thus it remains uncertain which cells are the main drivers of EAC. In contrast, ESCC is derived from squamous epithelial cells and appears to be driven by carcinogenic ...
Newer diagnostic modalities such as high resolution manometry help in predicting treatment response in achalasia based on esophageal pressure topography patterns identifying three phenotypes of achalasia (I-III) and outcome studies suggest better treatment response with types I and II compared to type III...