Acetyl L-carnitine en- hances acetylcholine release in the striatum and hippocampus of awake freely moving rats. Neurosci Lett 1989:107:251-5.Imperato, A, Ramacci, MT, Angelucci, L (1989) Acetyl-L-carnitine enhances acetylcholine release in the striatum and hippocampus of awake freely moving ...
Synthesis of [ 3 H]acetylcholine from [ 3 H]acetyl- l -carnitine was demonstrated in vitro by coupling the enzyme systems choline acetyltransferase and carnitine acetyltransferase. Likewise, both [ 3 H] and [ 14 C] labeled acetylcholine were produced when [ 3 H]acetyl- l -carnitine and d ...
Acetylcarnitine had no effect on voltage-activated Ca 2+ channel currents and glutamate-activated currents. Similar results were obtained in a dissociated cell culture preparation from the neonatal rat superior colliculus. In these cells acetylcholine induced a rightward shift in the dose - response ...
The process depicted here summarizes the synthesis, release, degradation and functions of ACh. Abbreviations: ACh, acetylcholine; AChE, acetylcholinesterase; acetyl-CoA, acetyl-coenzyme A; BChE, butyrylcholinesterase; CarAT, cardiac carnitine acetyltransferase; ChAT, choline acetyltransferase; ChT1, high ...
The pharmacology of d - and l - carnitine and d - and l -acetylcarnitine: comparison with choline and acetylcholine. J Pharmacol Exp Ther. 1971;178:331–338.Blum K, Seifter E, Seifter J (1971) The pharmacology of d - and l -carnitine and d - and l -acetylcarnitine: comparison with...
It should be noted that the observed reduction in the catalytic rate of ChAT in the L-phase is unlikely to be due to exhaustion of ChAT substrates (choline and acetyl-CoA), since ChAT activity remains unchanged for instance for TBS+TX100 (Figure 1A). We also investigated how a combination...