The acetyl-CoA transporter gene (Acatn) encodes a hydrophobic, multitransmembrane protein that is involved in the process of O-acetylation of sialic acid residues on gangliosides. O-Acetylated gangliosides have been found to play important roles in tissue development and organization during early ...
The acetyl-CoA transporter, AT-1 (also referred to as SLC33A1), is a key member of the endoplasmic reticulum (ER) acetylation machinery, transporting acetyl-CoA from the cytosol into the ER lumen where acetyl-CoA serves as the acetyl-group donor for Nε-lysine acetylation1,2. Gene duplica...
falciparum drug resistance genes, an acetyl-CoA transporter (pfact) and a UDP-galactose transporter (pfugt). Mutations were validated both in vitro by CRISPR editing in P. falciparum and in vivo by evolution of resistant Plasmodium berghei mutants. Both PfACT and PfUGT were localized to the ...
Here, we report the functional identification of acetyl-CoA transporter 1 (AT-1) as the ER membrane acetyl-CoA transporter. We show that AT-1 regulates the acetylation status of ER-transiting proteins, including the membrane proteins BACE1, low-density lipoprotein receptor and amyloid precursor ...
Acetyl-CoA transporter 1 antibody Basic informationMore.. Product Name:Acetyl-CoA transporter 1 antibody Synonyms: CAS: MF: MW:0 EINECS: Mol File:Mol File Information Error Report Your Email: Browse by NationalityAcetyl-CoA transporter 1 antibodySuppliersChina suppliers ...
查看相关系列 AcetylCoA transporter (1) 所有研究领域 Skip to the end of the images gallery Skip to the beginning of the images gallery 基本描述 别名 [¹⁴C]乙酰辅酶A 规格或纯度 Moligand™ 英文名称 [¹⁴C]acetylCoA 作用机制 乙酰辅酶 A 转运体 关联靶点(人) 名称和识别符 质检...
(ATP) production. Alternatively, citrate can be exported into the cytoplasm through the citrate transporter SLC25A1, where it can be converted back into acetyl-CoA by ATP-citratelyase(ACL). Cytoplasmic acetyl-CoA can be used for bothfatty acid synthesisand for protein acetylation. Thus it is ...
on conformational changes that we shall also cover. These are critical to developing a more complete understanding of life processes. I needed to lay out the scope of metabolic reactions and pathways, and their complementary changes. These may not appear to be adaptive, if the circumstances and ...
Metabolic engineering for supplying acetyl-CoA from fatty acid was manipulated by derepression of fadR (a major regulator that negatively controls the fatty acid degradative regulon) and constitutive expression of fadD (a transporter involved in the transport and activation of exogenous fatty acid). ...
Transporters with known molecular identity are indicated by circles. Steps of transmembrane passage with which no transporter has been identified with certainty are shown as diamonds, indicating an as-yet unknown transporter or non-transporter mediated passage. In all figures in this article, the ...