peroxisomes. HMG-CoAlyaseis found in peroxisomes and mitochondria. The entire conversion of acetyl-CoA to FPP occurs in the peroxisomes. The conversion of FPP tosqualeneoccurs only in the ER, while the conversion oflanosterolto cholesterol takes place in the ER and may also occur in the ...
The first category includes MKs inhibited by the metabolites downstream to PMD such as IPP, DMAPP, FPP, and longer chain terpenoids. This class of MKs is found in almost all plant and animal species, S. cerevisiae, and prokaryotes such as S. aureus and E. faecalis. On the other hand, ...