题目Synthesis of fatty acidsfrom acetyl CoA A. need NADPH B. need NAD+ C. produce malonyl CoAin the first step D. occur in mitochondria E. It's the reverse reactionsoffatty acidoxidation 相关知识点: 试题来源: 解析 AC 反馈 收藏
Fatty acid synthesis starts with the carboxylation of acetyl CoA to malonyl CoA byacetyl CoA carboxylase, with the consumption of ATP (Fig. 15.8). In a subsequent reaction, CoA is exchanged byacyl carrier protein(ACP) (Fig. 15.9). ACP comprises a serine residue to which a pantetheine is ...
Acetyl-CoA carboxylase (ACCase) catalyzes the synthesis of malonyl-CoA, the first intermediate in fatty acid synthesis. There are two forms of ACCase: a prokaryote form consisting of three protein components, biotin carboxylase, carboxyltransferase, and biotin carboxylase carrier protein, and a ...
Acetyl-CoA synthetase (ACS) enzyme carries an irreversible reaction that converts acetate to acetyl-CoA, which can be utilized directly for fatty acid synthesis, oxidized to carbon dioxide in tricarboxylic acid (TCA) cycle to make energy (ATP), or be converted in the glyoxylate cycle to succina...
Acetyl-CoA carboxylases (ACC) are rate-limiting enzymes in de novo fatty acid synthesis, catalyzing ATP-dependent carboxylation of acetyl-CoA to form malonyl-CoA. Malonyl-CoA is a critical bi-functional molecule, i.e., a substrate of fatty acid synthase (FAS) for acyl chain elongation (...
Malonyl-CoA, generated by acetyl-CoA carboxylases ACC1 and ACC2, is a key metabolite in the control of fatty acid synthesis and oxidation in response to dietary changes. ACC2 is associated to the mitochondria, and Acc2-/-mice have a normal lifespan and higher fatty acid oxidation rate and...
Acetyl-CoA carboxylases (ACCs) play a rate-limiting role in fatty acid biosynthesis in plants, microbes, mammals and humans. ACCs have the activity of both biotin carboxylase (BC) and carboxyltransferase (CT), catalyzing carboxylation of Acetyl-CoA to malonyl-CoA. In the past years, ACCs ...
smegmatis Acetyl-CoA Carboxylase M. smegmatis Fatty Acid Synthetase (Type I) Partial Reactions Catalyzed by M. smegmatis FAS M. smegmatis Synthetase Cataly... K Bloch - 《Adv Enzymol Relat Areas Mol Biol》 被引量: 207发表: 1977年 New malonyl-CoA-dependent fatty acid elongation system in ...
(malonyl-CoA) 乙醯輔酶A 丙二醯輔酶A A key intermediate in fatty acid biosynthesis是一種脂肪酸生合成的關鍵性中間產物 Acetyl-CoA carboxylase complex Biotin carboxylase生物素羧化酶 Catalyzed the transfer of carboxl group to biotin 催化羧基傳遞給生物素的反應 The activated “CO2” (from the ...
Acetyl-CoA carboxylase(ACCase) is a biotin-dependent enzyme that catalyzes the irreversible carboxylation of acetyl-CoA to produce malonyl-CoA,which is the key regulation step for fatty acid synthesis and oil accumulation. 植物的乙酰辅酶A羧化酶(ACCase)催化乙酰辅酶A羧化生成丙二酸单酰辅酶A,是脂肪...