chloroplasts contain a highly activeacetyl-CoA synthetase, which can convert acetate to acetyl-CoA upon consumption of ATP. In many plants,acetateis a major precursor for the formation of acetyl-CoA in chloroplasts and leucoplasts and may derive from priorhydrolysisof mitochondrial acetyl-CoA, forme...
After LCFAs are broken down first to medium-chain and finally to short-chain fatty acids such as acetoacetyl CoA, they must be converted in the liver to 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) before hydrolysis to acetoacetate, the ketone body used by the body for energy. Depending on ...
Nainamalai SitheswaranNigel T. PriceRona R. RamsaySpringer-VerlagMonatshefte Für ChemieN. Sitheswaran, N.T. Price, R.R. Ramsay, The G553M mutant of peroxisomal carnitine octanoyltransferase catalyses acetyl transfer and acetyl-CoA hydrolysis, Monatsh. Chem. -- Chemical Monthly 136 (2005) 1341...
Haagen L et al (1992) A new automated method for phe- notyping arylesterase (EC 3.1.1.2) based upon inhibition of enzymatic hydrolysis of 4-nitrophenyl acetate by phenyl acetate. Eur J Clin Chem Clin Biochem 30:391–395 Xu GY et al (2005) Monitoring the level of serum paraoxonase 1 ...
Lack of nutrients, in particular nitrogen and phosphorus, has been known in the field to sense glutamate production via 2-oxoglutarate and subsequently accelerate carbon storage, including glycogen and polyhydroxybutyrate (PHB), in cyanobacteria, but a f
Carnitine is important in the β-oxidation of fatty acids and the acetyl moiety can be used to maintain acetyl-CoA levels. Other reported neurobiological effects of ALCAR include modulation of: (1) brain energy and phospholipid metabolism; (2) cellular macromolecules, including neurotrophic factors ...
products and derivatives inactivate homoserine transacetylase, a target for antimicrobial agents Gianfranco De Pascale1, Ishac Nazi1, Paul HM Harrison2 and Gerard D Wright1 Homoserine transacetylase (HTA) catalyzes the transfer of an acetyl group from acetyl-CoA to the hydroxyl group of homoserine...
filtration, sterilization, hydrolysis, purification and other processes Shelf time2 years,keep away sunlight, keep dry Send inquiry details and get a Free Sample Product advantages: (1)High product purity, over 99%; (2)Uniform granularity, can also be customized accor...
The native PDH-bypass reaction for forming acetyl-CoA is thermodynamically favorable because the reaction is coupled to the hydrolysis of ATP to AMP. In contrast, the ADA reaction is not coupled to ATP, and is much closer to equilibrium than the native PDH-bypass reactions for forming Acetyl-...
The present invention relates to compounds of formula (I) which inhibit acetyl-CoA carboxylase (ACC) and are useful for the prevention or treatment of metabolic syndrome, type II diabetes, obesity, atherosclerosis and cardiovascular diseases in humans.Inventors...