Weihua Tang,Siu-Choon Ng,Hardy Sze On Chan.Asymmetric Reduction of Acetophenones with NaBH4 in the Presence of Mono-6-(1-methyl-3-imidazolium)-6-deoxy-β-cyclodextrin Tosylate[J]. Journal of Inclusion Phenomena and Macrocyclic Chemistry .2006(3-4)...
The reduction of 2-CAP prod... JM Smolen,EJ Weber,PG Tratnyek - 《Environmental Science & Technology》 被引量: 23发表: 1999年 Chiral styrene oxides from α-haloacetophenones using NaBH4 and TarB-NO2, a chiral Lewis acid High enantioselectivities are obtained for the preparation of chiral...
Jiang et al., 2000, “Highly enantioselective reduction of achiral ketones with NaBH4/Me3SiCl catalyzed by (S)-α,α-diphenylpyrrolidinemethanol,” Tetrahedron Letters 41:10281-10283. Jones et al., 1981, “Enzymes in organic syntheses. 19.1 Evaluation of the stereoselectivities of horse liver...
Mild and Efficient Deoxygenation of Amine-N-Oxides with FeCl3·6H2O-Indium System under Ultrasonication We believe that the mild and efficient method described here will present an attractive alternative to the existing methods available for the reduction of ... BW Yoo,KH Sun,YK Dong,... - 《...
Substituent effects in the enantioselective reduction of acetophenones with nabh4 in the presence of β‐cyclodextrin The effect of substituent groups on asymmetric induction by -cyclodextrin (-CD) was investigated in the reduction of a series of o -, m -, and p -substi... E Renard - 《...
We have shown the possibility of enantiomeric induction in the reduction of prochiral ketones by NaBH4 supported on a chiral support. The supports involved polymers (porous or gel type) containing chiral amino-alcohol groups in the side chain. Three chemical ways were tested to obtain these types...
of Aryltrimethylsilyl Chiral Alcohols 2a–f 1-(Bromo-phenyl)ethanols 1a–f were synthesized in excellent yields (90–92%) by reacting o-, m-, and p-bromo-substituted acetophenones with NaBH4 (Scheme 1) =-=[35]-=-. Scheme 1. Reduction of bromo-substituted acetophenones to afford ...
Despite the similarities in chemical structure, only the imine derived from (S)-NOBIN and 2-pyridinecarbaldehyde and the corresponding amine (obtained by NaBH4 reduction of the imine) afforded (S)-1-phenylethanol in nearly quantitative yields and outstanding enantioselectivities of up to 97% e.e....
derivativesThe general route involves aldol condensation of salicylaldehydes with acetophenones and reduction of both the ketone and the double bond of the resulting chalcones with NaBH4.OfentseDep.MazimbaDep.IshmaelDep.B.Dep.MaseaneDep.RunnerDep.R....
Here we firstly developed a green, simple and potential epoxidation system by enantioselective reduction of a-haloacetophenones using NaBH4 in water.The procedure of the unexpected epoxidation was firstly found accidentally in the study of L-proline-catalyzed asymmetric reduction of aldehydes, ketones...