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doi:10.1038/s41422-020-00438-wCryoelectron microscopyMolecular biologyLiang GuoWenwen BiRenhong YanYuanyuan ZhangKai ZhaoYaning LiMingfeng ZhangQiang ZhouBobo DangXinling WangCell Research
The formation process of N-glycosylation and O-glycosylation in SARS-CoV-2. According to the complexity of the glycans, the N-glycosylation (a) is classified into oligomannose-type (2HexNAc), hybrid-type (3HexNAc), and complex-type (with more than 3HexNAc) glycans, whereas the mucin O-...
SARS-CoV-2 binds to angiotensin-converting enzyme 2 (ACE2), a key viral entry receptor on the host cell through spike (S) glycoprotein located on the surface of the virus [12, 13]. The entry of the virus into the host cells is also mediated by host proteases such as trans- membrane...