Existing SNP-heritability estimators that leverage summary statistics from genome-wide association studies (GWAS) are much less efficient (i.e., have larger standard errors) than the restricted maximum likelihood (REML) estimators which require access to
"The data indicating this approach can be used to distinguish SARS-CoV-2 variants of concern by differential detection of genomic mutations could enable us to better prepare for the appearance of the next mutation," said Tony Hu, director of the Center for Intelligent Molecular Diagnostics and We...
Holographic solutions can thus serve as capable tools for particle tracking (PT)5 that is crucial in, e.g., analyzing cell biophysical processes6, flow measurements7, optofluidics8, microfluidics9, point-of-care diagnostics10 and optical manipulation11, as “particle” can mean any object from ...
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The requirement to precisely estimate\({F}_{\mathrm{DEP}}\)induced on particles is critical in the development of efficient microfluidic systems.\({F}_{\mathrm{DEP}}\)estimation is a necessity in DEP aided dielectric characterization systems used in clinical diagnostics of biological cells32. Pa...
users with a new level of “process information” for localised viewing of wet gas flow data. This instrument offers the industry’s most comprehensive information with continuous display of all process measurement...
Transferable, easy-to-use and room-temperature-storable PCR mixes for microfluidic molecular diagnostics 2021, Talanta Citation Excerpt : In this study, a freeze-drying method was established to produce microfluidic applicable PCR reagents using pipettes and liquid nitrogen (Fig. 2A). All components ...
The most common blood tests used as first line for diagnostics and monitoring patients' status, always include blood electrolytes, iron, and in some cases, heavy metals. The present work investigates the formation of rapidly solidified Homogeneous Thin Solid Films (HTSFs) formed from blood drops,...
For robots with more than two steerable wheels the system also has inherent redundancy that enables diagnostics of vehicle motion estimation based on wheel motions. Robustness. Steerable wheels are relatively robust to floor and environment conditions, and vehicle motion control is maintained even if ...
CRISPR/Cas12a, from the type V-A CRISPR system, exhibits site-specific dsDNA cutting and nonspecific ssDNA trans-cleavage ability, which provides an efficient signal amplification tool for molecular diagnostics [19]. LAMP-binding CRISPR/Cas system has been applied in the field of disease ...