The critical event controlling maleness is the expression of the sex-determining gene (Sry); this in turn elicits a whole cascade of events to enable the fetal gonad to develop into a testis. Other genes implicated in the normal differentiation of the male reproductive system include, but are...
Transcriptional profiling of XdrA, a new regulator of spa transcription in Staphylococcus aureus. NorthernBlottingWesternDNA-Binding ProteinsGene Expression RegulationBacterialHemolysisTranscription of spa, encoding the virulence factor protein A in Staphylococcus ... N Mccallum,J Hinds,M Ender,... - 《...
The selection of specific inhibitors of the SarA protein is made possible as a result of the identification of the binding sites of SarA protein on at least a portion of the agr (accessory gene regulator) gene, a gene that like the sar (staphylococcal accessory regulator) gene, plays a ...
et al. Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis. Proc Natl Acad Sci USA 110, 7434–7439, doi: 10.1073/pnas.1213050110 (2013). Article ADS PubMed PubMed Central Google Scholar Behrens, M. et al. Members of RTP...
The other natural regulator of IL-1 action is the type II IL-1 receptor McMahan et al. 1991, Colotta et al. 1993. Although this protein binds tightly to IL-1β, it lacks a cytoplasmic domain and cannot signal; it therefore functions as a decoy receptor. The type II IL-1R also ...
Growth hormone (GH), a major regulator of normal body growth and metabolism, regulates cellular gene expression. The transcription factors Elk-1 and Serum ... C Hodge,J Liao,M Stofega,... - 《Journal of Biological Chemistry》 被引量: 787发表: 1998年 The ETS Domain Transcription Factor El...
Synthetic biology confers new functions to hosts by introducing exogenous genetic elements, yet rebuilding complex traits that are based on large-scale genetic information remains challenging. Here, we developed a CRISPR/Cas9-mediated haploidization meth
Necroptosis is actively inhibited by a supramolecular complex containing CASP8, FADD and the long isoform of CASP8 and FADD-like apoptosis regulator (CFLAR, best known as cellular FLICE inhibitor protein, c-FLIP),194, 195, 196, 197 three key components of caspase-dependent RCD initiated by dea...
QIAGEN 37900 Qproteome Bacterial Protein Prep Kit QIAGEN 9015337 Regulator, DC5V QIAGEN 9015323 O-rings, plunger fixing, M48 (6) QIAGEN 133035 NeXtalStock Ammonium phosphate (200) QIAGEN 133033 NeXtalStock Cobalt(II) Chloride (200) QIAGEN 9001637 Rotor-Gene Q 2plex HRM (w/o PC) System ...
ClpS is a regulator protein which seems to be the substrate selector for the Clp system in chloroplasts of A. thaliana[19]. ClpT1 and ClpT2 are small proteins exclusively found in plants. Initially, they were annotated as nClpC-like proteins, due to their homology to the N-terminus of ...