The dark brown solution was then refluxed for 16 hours. Ethanol was removed and the aqueous phase was acidified with 2N HCl and extracted with ethyl acetate (3×200 mL). The combined organic layers were washed with brine, dried (MgSO4) and filtered. The filtrate was concentrated in vacuo ...
ACC006口服溶液的适应症是晚期非小细胞肺癌。 此药物由扬州艾迪生物科技有限公司/ 南京安赛莱医药科技有限公司/ 中国药科大学生产并提出实验申请,[实验的目的] 主要目的是评价非小细胞肺癌患者使用ACC006联合特瑞普利单抗的耐受性和安全性。 文章目录[隐藏] 基本信息 公示的试验信息 基本信息 公示的试验信息 一、题目...
ACC006中文名可能是艾索康唑,有可能是3羟基-伊曲康唑,可能的作用机制是抑制血管内皮细胞的增殖、迁移、趋化及管腔的形成,本试验适应症是晚期实体瘤。 公示的试验信息 一、题目和背景信息 1、试验目的三、临床试验信息 主要目的是评价非小细胞肺癌患者使用ACC006联合特瑞普利单抗的耐受性和安全性。 2、试验设计 3、...
该共识强调,对于经历过需要中断抗凝治疗的出血事件的患者,医患之间应充分讨论重新应用口服抗凝药物的获益和风险。 来源:2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Solution Set Oversight Committee. J Am...
2016-06-19上传 Accccaaaddddeeeemmmmiiiccc SSSScccciiiieeeennnncccceeessss AA… 文档格式: .pdf 文档大小: 219.73K 文档页数: 8页 顶/踩数: 0/0 收藏人数: 0 评论次数: 0 文档热度: 文档分类: 论文--期刊/会议论文 文档标签: AccccaaaddddeeeemmmmiiicccSSSScccciiiieeeennnncccceeessssAA ...
An option is to consider double therapy—the use of an oral anticoagulant plus a P2Y12 inhibitor without aspirin (S7.4-3). If triple therapy is used, efforts may be directed to minimize duration of triple therapy to a period of 4 to 6 weeks, as this is the period of greatest risk of...
The percutaneous LD50 of male rats was 21mg/kg, and the female was 6.8mg/kg; the lowest lethal dose in rats was 10 mg/m3. The oral no-effect dose was 2 mg/kg per day in rats and 1 mg/kg per day in dogs. The avian acute oral LD50 is 2 mg/kg. Carp LC50 4.5mg/L(48h)....
a Immunohistochemistry shows that the l-carnitine group showed a significant upregulation of CPT1 compared with the ACLT group (positive cells are shown with blue arrows, × 200 magnification, n = 6). b Immunoblot and densitometric analysis of CPT1 (n = 3). c Real-time PCR ...
e. 200 mg/kg b. w.13. 2.8 Oral Glucose Tolerance Test (OGTT) Fasting blood glucose level of each rat was determined at zero time after overnight fasting with free access to water only. Rats were divided into three groups containing six rats in each. Group-I (Control group) ...
Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome characterized by diffuse hepatocellular steatosis due to fatty deposits in hepatocytes, excluding alcohol and other known liver injury factors. However, there are no specific dru