This thrice-daily dosing may limit adherence in many patients. Side effects of acamprosate include diarrhea in as many as 16% of patients, but it is otherwise usually well-tolerated. This medication is safe to use in patients with moderate liver disease (Child-Pugh class A or B cirrhosis),...
Franko, PharmD Common Brand Name(s): Campral Common Generic Name(s): acamprosate, acamprosate Ca, acamprosate calcium Pronunciation: a-KAM-pro-sate Drug Classes: gamma-aminobutyric acid (GABA) analog Availability: prescription only, generic available How is it used? tablet that is swallowed...
Novel research design decisions were informed by basic science and European clinical studies and include: 1.) an exploratory study of a 3 gram dosing condition based on the absence of rate-limiting side effects in a standard 2 gram dose; 2.) a 500 mg dosage strength, with a b.i.d. ...
Gastric retentive dosage forms for sustained release of acamprosate are described which may allow once- or twice-daily dosing for both acute and long-term treatment of a disorder including alcohol dependence, tinnitus, sleep apnea, Parkinson's disease, levodopa-induced dyskinesias in Parkinson's ...
This work engross the study of pharmacokinetic property of Acamprosate calcium tablets in single dosing under fasting condition. Methods: Bioequivalence study of delayed release acamprosate tablets 333 mg for a randomized, single dose, open label, two treatment, two periods, two sequences and cross...