Acamprosate (Campral EC-Lipha) was launched in the UK in 1996 to be used, with counselling, in maintaining abstinence after alcohol withdrawal in patients with known dependence. Here we review its effects.BMJDrug & Therapeutics Bulletin
A dose reduction is recommended in patients with renal impairment. No clinically meaningful between-group differences were reported for clinical chemistry tests or vital sign parameters. This ad hoc analysis demonstrates that acamprosate can be used safely in alcohol-dependent patients, includ...
Alcohol misuse accounts for a sizeable proportion of the global burden of disease, and Campral® (acamprosate; calcium-bis-(N-acetylhomotaurinate)) is widely used as relapse prevention therapy. The mechanism underlying its effect has in some studies be
acamprosate,accordin,alcohol abuse,alcohol dependence,alcohol dependency treatment,alcohol treatment,behavioral health,behavioral interventions,campral,car accidents,criminal justice research,d vice,dependent individuals,effect of alcohol,health care costs,journal medical,leading preventable cause,medication therapy...
Le Magnen J, Tran G, Durlach J, Martin C (1987) Dose-dependent suppression of the high alcohol intake of chronically intoxicated rats by Ca-acetylhomotaurinate. Alcohol 4(2): 97–102 PubMed Google Scholar Gewiss M, Heidbreder C, Opsomer L, Durbin P, De Witte P (1991) Acamprosate...
(2000b): A multicentre, randomized, double-blind, placebo-controlled trial of naltrexone in the treatment of alcohol dependence or abuse. Alcohol Alcohol 35: 587–593 CAS PubMed Google Scholar Cohen RM, Cohen MR, Weingartner H, Pickar D, Murphy DL . (1983): High-dose naloxone affects ...
individuals with alcohol dependence, under DSM‐IV‐TR/ICD‐10acamprosate, as adjunctive to psychosocial/psychotherapeuticacamprosate and naltrexone comparison, for relative effectivenessdoi:10.1002/9781118454503.ch12Iosief AbrahaCristina CusiJohn Wiley & Sons, Ltd...
Reports on the drug approval for acamprosate by the Food and Drug Administration in the U.S. Use of the drug for the treatment of alcohol dependence; Safety and efficacy of the drug; Significance of the drug approval.EBSCO_AspAlcoholism & Drug Abuse Weekly...
Acamprosate received approval by the US FDA for the treatment of alcohol dependence in July 2004 and is currently prescribed in 28 countries.doi:10.1517/14656566.6.12.2103MasonBarbara JExpert Opinion on PharmacotherapyMason B. Acamprosate in the treatment of alcohol dependence. Expert Opinion on ...
ACAMPROSATE AND NALTREXONE FOR ALCOHOL DEPENDENCE: RESULTS FROM COCHRANE REVIEWS6 Results: The fatty acid amide hydrolase (FAAH) inhibitor uRB597 dose dependently blocks ongoing nicotine self-administration and reinstatement of extinguished nicotine-seeking behavior in squirrel monkeys. The blockade of ...