Acamprosate (calcium acetylhomotaurinate), a synthetic compound with a similar chemical structure to that of γ-aminobutyric acid, is thought to act via several mechanisms affecting multiple neurotransmitter systems; inhibition of neuronal hyperexcitability by antagonism of excitatory amino acid activity an...
Acamprosate (calcium-acetyl homotaurinate) is a synthetic derivative of taurine that is used to treat relapse in alcohol-dependent patients. It is also effective in animal models of alcoholism. Acamprosate suppresses the ADE in two-bottle choice and operant self-administration designs. It has also...